IFIT3 and IFIT1B

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid, affinity chromatography technology)

		IFIT3	IFIT1B
Name		interferon induced protein with tetratricopeptide repeats 3	interferon induced protein with tetratricopeptide repeats 1B
Structure			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	RNA Binding Protein Binding RNA Sequestering Activity
	Biological Process	Immune System Process Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Apoptotic Process Innate Immune Response Defense Response To Virus Antiviral Innate Immune Response	Defense Response To Virus Response To Other Organism Negative Regulation Of Viral Translation
Pathways		Interferon alpha/beta signaling	None
GWAS		Hormone measurements ( 30576415 )	No GWAS studies recorded
Interacting Genes		21 interacting genes: A2M ANXA1 APOE CYP2C8 DEUP1 ECSIT FANCA HAUS1 IFIT1 IFIT1B IFIT2 IFIT5 LONP1 LVRN MAST1 PSEN2 RAD23A RNF32 TMEM183A TPM1 TPM3	1 interacting genes: IFIT3
Entrez ID		3437	439996
HPRD ID		05228	17129
Ensembl ID		ENSG00000119917	ENSG00000204010
Uniprot IDs		A0A7P0T7D6 O14879 Q5T765	Q5T764
PDB IDs		6C6K	Not available
GO Terms Enriched among Interactors		Negative Regulation Of Viral Translation RNA Sequestering Activity Muscle Thin Filament Tropomyosin Regulation Of Viral Process Response To Stress Negative Regulation Of Viral Process Regulation Of Viral Genome Replication Actin Filament Amyloid Precursor Protein Metabolic Process Defense Response To Virus Regulation Of Viral Life Cycle Innate Immune Response Negative Regulation Of Phospholipid Efflux Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Metal Chelating Activity Intermediate-density Lipoprotein Particle Clearance Response To Virus Positive Regulation Of Viral Genome Replication Positive Regulation Of Heart Rate By Epinephrine Oxidation-dependent Protein Catabolic Process	None