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UXT

Name ubiquitously expressed prefoldin like chaperone
Structure No pdb structure
Interactors 29 interactors: APP AR CECR2 DYNLT1 GLE1 KRT31 KRT40 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP5-7 KRTAP5-9 LRPPRC LSM1 MACROD1 MCPH1 MPP1 NBPF19 NOTCH2NLA PAK5 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 TXNIP VHL
GO Annotations Cellular Component
  • Chromatin
  • Spindle Pole
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Centrosome
  • Cytoskeleton
  • Mediator Complex
  • Protein-containing Complex
  • Protein Folding Chaperone Complex
  • RPAP3/R2TP/prefoldin-like Complex
Molecular Function
  • Chromatin Binding
  • Transcription Corepressor Activity
  • Protein Binding
  • Microtubule Binding
  • Beta-tubulin Binding
  • Actin Filament Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Microtubule Cytoskeleton Organization
  • Apoptotic Process
  • Centrosome Cycle
  • Mitochondrion Transport Along Microtubule
  • Protein Stabilization
Pathways
  • Transcriptional Regulation by E2F6
GWAS No GWAS studies recorded
Entrez ID 8409
HPRD ID 02209
Ensembl ID ENSG00000126756
Uniprot IDs Q9UBK9
PDB IDs Not available
GO Terms Enriched among Interactors ?
  • Intermediate Filament
  • Keratin Filament
  • Amyloid Fibril Formation
  • Identical Protein Binding
  • Supramolecular Fiber Organization
  • Structural Constituent Of Skin Epidermis

© Madhavi K. Ganapathiraju 2012-2026