SRP72

Name	signal recognition particle 72
Structure
Novel Interactors	2 novel interactors: EDN2 KDR
Interactors	12 interactors: CASP3 CASP6 CDC42 CEBPA FCHSD2 HSPB1 OGT PYGM SKIL SRP68 SULT2B1 TULP3
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Signal Recognition Particle Ribonucleoprotein Complex
	Molecular Function	RNA Binding Signal Recognition Particle Binding Protein Binding 7S RNA Binding TPR Domain Binding Ribosome Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane
Pathways	SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane
GWAS	Airflow obstruction ( 22837378 )
Entrez ID	6731
HPRD ID	03671
Ensembl ID	ENSG00000174780
Uniprot IDs	O76094 V9HWK0
PDB IDs	5M72 5M73 5WRV 5WRW 7NFX 8QVW 8QVX
GO Terms Enriched among Interactors ?	Cellular Response To Staurosporine Pyroptotic Inflammatory Response Epithelial Cell Differentiation Multicellular Organismal-level Homeostasis Endothelin Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Positive Regulation Of Endothelial Cell Chemotaxis Protein-containing Complex Binding Epithelial Cell Maturation Positive Regulation Of Chemotaxis Intracellular Signal Transduction Cellular Response To Vascular Endothelial Growth Factor Stimulus Regulation Of Necroptotic Process Embryonic Organ Development Cellular Response To Alkaloid Signal Transduction Intrinsic Apoptotic Signaling Pathway Anatomical Structure Formation Involved In Morphogenesis Homeostatic Process Protein Processing Regulation Of Programmed Necrotic Cell Death Positive Regulation Of Developmental Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Phosphatidylinositol-3,4,5-trisphosphate Binding Regulation Of Programmed Cell Death Cytoplasm Epithelial Cell Apoptotic Process Inflammatory Response Cellular Developmental Process Response To Cytokine Positive Regulation Of Organelle Organization Regulation Of Cell Migration Macrophage Differentiation Protein Domain Specific Binding RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Cell Tip Growth Hormonal Regulation Of The Force Of Heart Contraction Regulation Of Chemotaxis Lung Alveolus Development Negative Regulation Of Protein Kinase C Signaling Positive Regulation Of Nitric Oxide-cGMP Mediated Signal Transduction Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Stereocilium Shaft Epithelium Development Regulation Of Multicellular Organismal Process Positive Regulation Of Cell Migration Response To Peptide Regulation Of Cell Motility Vasculature Development