TNFSF15 and TNFRSF6B

Number of citations of the paper that reports this interaction (PMID 11911831)
105

Data Source:
HPRD (in vivo)

		TNFSF15	TNFRSF6B
Gene Name		tumor necrosis factor (ligand) superfamily, member 15	tumor necrosis factor receptor superfamily, member 6b, decoy
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Extracellular Space
	Molecular Function	Receptor Binding Death Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding	Receptor Activity Protein Binding
	Biological Process	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Immune Response Signal Transduction Activation Of NF-kappaB-inducing Kinase Activity Cytokine Metabolic Process Positive Regulation Of Cytokine Secretion	Apoptotic Process Negative Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 18587394 21102463 23266558) Inflammatory bowel disease ( 18758464 23128233 21699788) Leprosy ( 20018961) Primary biliary cirrhosis ( 23000144) Ulcerative colitis ( 20848476 21297633)	Glioma ( 22886559) Inflammatory bowel disease ( 18758464 23128233) Prostate cancer ( 23535732) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		2 interactors: TNFRSF25 TNFRSF6B	5 interactors: FASLG KRTAP10-3 KRTAP10-9 TNFSF14 TNFSF15
Entrez ID		9966	8771
HPRD ID		04956	04527
Ensembl ID		ENSG00000181634	ENSG00000243509
Uniprot IDs		O95150	O95407
PDB IDs		2O0O 2QE3 2RE9 2RJK 2RJL 3K51 3MI8	3K51 3MHD 3MI8 4J6G 4KGG 4KGQ
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Apoptotic Process Regulation Of Cell Death Cellular Response To Tumor Necrosis Factor Response To Tumor Necrosis Factor	Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Endopeptidase Activity Regulation Of Peptidase Activity Regulation Of Proteolysis Positive Regulation Of Intracellular Signal Transduction Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Programmed Cell Death Positive Regulation Of Cysteine-type Endopeptidase Activity Cell Death Death Positive Regulation Of Endopeptidase Activity Positive Regulation Of Peptidase Activity Positive Regulation Of Signal Transduction Immune Response Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Cell Death Protein Processing Endosomal Lumen Acidification Regulation Of Intracellular Signal Transduction Retinal Cell Programmed Cell Death Positive Regulation Of Proteolysis Release Of Cytoplasmic Sequestered NF-kappaB Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Transport Necroptotic Signaling Pathway Immune System Process Regulation Of Protein Metabolic Process Cellular Chloride Ion Homeostasis Inflammatory Cell Apoptotic Process Regulation Of Catalytic Activity Positive Regulation Of T Cell Chemotaxis Chloride Ion Homeostasis Positive Regulation Of Endothelial Cell Apoptotic Process Regulation Of Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Protein Transport T Cell Apoptotic Process Positive Regulation Of Myoblast Differentiation Positive Regulation Of T Cell Migration Positive Regulation Of Myoblast Fusion Regulation Of Signaling
Tagcloud ?		5httlpr 7alpha ba cholesten colonic constipation ct48 fdr fecal fgf19 fgfr4 gpbar1 ibs insert irritable klb multifaceted pathobiological pathobiology predisposing reuptake rs11554825 rs17618244 rs351855 rs4263839 rs4795541 sensation slc6a4 transit	adjacent bioinformatics blotting clarified clinicopathological deregulation dnmt1 downregulated embedded fluorimetry formalin genesis hcc hepatocarcinogenesis hepb3 hepg2 intriguingly inverse mimic mir motility paraffin remarkably snu449 spectrophotometry underexpression vital
Tagcloud (Difference) ?		5httlpr 7alpha ba cholesten colonic constipation ct48 fdr fecal fgf19 fgfr4 gpbar1 ibs insert irritable klb multifaceted pathobiological pathobiology predisposing reuptake rs11554825 rs17618244 rs351855 rs4263839 rs4795541 sensation slc6a4 transit	adjacent bioinformatics blotting clarified clinicopathological deregulation dnmt1 downregulated embedded fluorimetry formalin genesis hcc hepatocarcinogenesis hepb3 hepg2 intriguingly inverse mimic mir motility paraffin remarkably snu449 spectrophotometry underexpression vital
Tagcloud (Intersection) ?