TNFSF15

Gene Name		tumor necrosis factor (ligand) superfamily, member 15
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Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Receptor Binding Death Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding
	Biological Process	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Immune Response Signal Transduction Activation Of NF-kappaB-inducing Kinase Activity Cytokine Metabolic Process Positive Regulation Of Cytokine Secretion
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 18587394 21102463 23266558) Inflammatory bowel disease ( 18758464 23128233 21699788) Leprosy ( 20018961) Primary biliary cirrhosis ( 23000144) Ulcerative colitis ( 20848476 21297633)
Protein-protein Interactions		2 interactors: TNFRSF25 TNFRSF6B
Entrez ID		9966
HPRD ID		04956
Ensembl ID		ENSG00000181634
Uniprot IDs		O95150
PDB IDs		2O0O 2QE3 2RE9 2RJK 2RJL 3K51 3MI8
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Apoptotic Process Regulation Of Cell Death Cellular Response To Tumor Necrosis Factor Response To Tumor Necrosis Factor
Tagcloud ?		5httlpr 7alpha ba cholesten colonic constipation ct48 fdr fecal fgf19 fgfr4 gpbar1 ibs insert irritable klb multifaceted pathobiological pathobiology predisposing reuptake rs11554825 rs17618244 rs351855 rs4263839 rs4795541 sensation slc6a4 transit