RBM8A and UPF3A

Number of citations of the paper that reports this interaction (PMID 11546873)
80

Data Source:
HPRD (in vivo)

		RBM8A	UPF3A
Gene Name		RNA binding motif protein 8A	UPF3 regulator of nonsense transcripts homolog A (yeast)
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Exon-exon Junction Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Nucleotide Binding RNA Binding MRNA Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding Nucleocytoplasmic Transporter Activity Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus Regulation Of Translation RNA Splicing Gene Expression MRNA 3'-end Processing	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nucleocytoplasmic Transport Gene Expression Positive Regulation Of Translation MRNA Transport
Pathways		Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing	Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: APP DPH1 EIF4A3 FBXO25 IKBKG IPO13 MAGOH MAGOHB MCM7 NXF1 RNPS1 SF3B2 SRPK1 SRPK2 TOE1 UPF3A UPF3B	9 interactors: ALYREF APP GSK3B IFITM2 NXF1 PIGT RBM8A SMG1 UPF1
Entrez ID		9939	65110
HPRD ID		05609	09274
Ensembl ID		ENSG00000131795	ENSG00000169062
Uniprot IDs		Q9Y5S9	B3KUE7 Q9H1J1
PDB IDs		1P27 2HYI 2J0Q 2J0S 2XB2 3EX7	2L08
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Transport MRNA Processing RNA Transport RNA Localization RNA Splicing RNA Processing MRNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA 3'-end Processing Nucleocytoplasmic Transport Nuclear Transport Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process MRNA Export From Nucleus Gene Expression RNA Catabolic Process Regulation Of MRNA Splicing, Via Spliceosome RNA Export From Nucleus Regulation Of MRNA Processing Regulation Of RNA Splicing RNA Metabolic Process Regulation Of Translation Nuclear Export Nucleobase-containing Compound Metabolic Process Termination Of RNA Polymerase II Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cytoplasmic Transport Cellular Nitrogen Compound Metabolic Process Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression DNA-templated Transcription, Termination Positive Regulation Of Translation Nitrogen Compound Metabolic Process Establishment Of Localization In Cell Intracellular Transport Cellular Localization Positive Regulation Of Viral Genome Replication Regulation Of Alternative MRNA Splicing, Via Spliceosome Cellular Macromolecule Catabolic Process Cellular Metabolic Process Positive Regulation Of Gene Expression Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Viral Process Negative Regulation Of Viral Genome Replication Positive Regulation Of Cellular Protein Metabolic Process Nuclear Speck Organization	Nuclear Export MRNA Export From Nucleus RNA Export From Nucleus Nucleocytoplasmic Transport Nuclear Transport MRNA Transport RNA Transport RNA Localization Cytoplasmic Transport Intracellular Transport MRNA Metabolic Process Establishment Of Localization In Cell MRNA 3'-end Processing Cellular Localization Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Termination Of RNA Polymerase II Transcription Regulation Of Translation Neuron Apoptotic Process Neuron Death DNA-templated Transcription, Termination Transport MRNA Processing Aromatic Compound Catabolic Process Response To Stress Gene Expression Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Type B Pancreatic Cell Development Synaptic Growth At Neuromuscular Junction Superior Temporal Gyrus Development Peptidyl-serine Phosphorylation RNA Processing Re-entry Into Mitotic Cell Cycle Collateral Sprouting In Absence Of Injury Negative Regulation Of Neuron Maturation Regulation Of Protein Binding Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Cellular Response To Stress Collateral Sprouting Axon Midline Choice Point Recognition Cellular Response To Interleukin-3 Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Neuron Differentiation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Glycogen (starch) Synthase Activity Axon Choice Point Recognition
Tagcloud ?		appearance bodies casc3 core correlate correlates cytoplasm cytoplasmic deregulation determining disassembly eif4aiii ejc exon fate foci granules junction loaded localizes magoh mln51 movements onto overexpressed overexpressing spliced unlike y14
Tagcloud (Difference) ?		appearance bodies casc3 core correlate correlates cytoplasm cytoplasmic deregulation determining disassembly eif4aiii ejc exon fate foci granules junction loaded localizes magoh mln51 movements onto overexpressed overexpressing spliced unlike y14
Tagcloud (Intersection) ?