UPF3A

Gene Name		UPF3 regulator of nonsense transcripts homolog A (yeast)
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Exon-exon Junction Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Nucleotide Binding RNA Binding Nucleocytoplasmic Transporter Activity Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nucleocytoplasmic Transport Gene Expression Positive Regulation Of Translation MRNA Transport
Pathways		Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-protein Interactions		9 interactors: ALYREF APP GSK3B IFITM2 NXF1 PIGT RBM8A SMG1 UPF1
Entrez ID		65110
HPRD ID		09274
Ensembl ID		ENSG00000169062
Uniprot IDs		B3KUE7 Q9H1J1
PDB IDs		2L08
Enriched GO Terms of Interacting Partners?		Nuclear Export MRNA Export From Nucleus RNA Export From Nucleus Nucleocytoplasmic Transport Nuclear Transport MRNA Transport RNA Transport RNA Localization Cytoplasmic Transport Intracellular Transport MRNA Metabolic Process Establishment Of Localization In Cell MRNA 3'-end Processing Cellular Localization Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Termination Of RNA Polymerase II Transcription Regulation Of Translation Neuron Apoptotic Process Neuron Death DNA-templated Transcription, Termination Transport MRNA Processing Aromatic Compound Catabolic Process Response To Stress Gene Expression Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Type B Pancreatic Cell Development Synaptic Growth At Neuromuscular Junction Superior Temporal Gyrus Development Peptidyl-serine Phosphorylation RNA Processing Re-entry Into Mitotic Cell Cycle Collateral Sprouting In Absence Of Injury Negative Regulation Of Neuron Maturation Regulation Of Protein Binding Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Cellular Response To Stress Collateral Sprouting Axon Midline Choice Point Recognition Cellular Response To Interleukin-3 Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Neuron Differentiation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Glycogen (starch) Synthase Activity Axon Choice Point Recognition
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