UPF3A and PIGT

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		UPF3A	PIGT
Description		UPF3A regulator of nonsense mediated mRNA decay	phosphatidylinositol glycan anchor biosynthesis class T
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Exon-exon Junction Complex Neuron Projection	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Cytoplasmic Vesicle GPI-anchor Transamidase Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Telomeric DNA Binding	Protein Binding GPI Anchor Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay In Utero Embryonic Development Spermatogenesis Positive Regulation Of Translation MRNA Transport Positive Regulation Of MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay	GPI Anchor Biosynthetic Process Attachment Of GPI Anchor To Protein Neuron Differentiation Neuron Apoptotic Process GPI Anchored Protein Biosynthesis
Pathways		Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Attachment of GPI anchor to uPAR
Drugs
Diseases
GWAS		Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Nodular sclerosis Hodgkin lymphoma ( 29196614) Pulse pressure ( 30578418)	Malaria ( 31844061)
Interacting Genes		9 interacting genes: ALYREF APP GSK3B IFITM2 NXF1 PIGT RBM8A SMG1 UPF1	3 interacting genes: GPAA1 PIGK UPF3A
Entrez ID		65110	51604
HPRD ID		09274	15136
Ensembl ID		ENSG00000169062	ENSG00000124155
Uniprot IDs		B3KUE7 Q9H1J1	Q969N2
PDB IDs		2L08 7QG6	7W72 7WLD 8IMX 8IMY
Enriched GO Terms of Interacting Partners?		MRNA Export From Nucleus RNA Export From Nucleus Nuclear Export MRNA Transport RNA Transport Nucleobase-containing Compound Transport Nuclear Transport Nucleocytoplasmic Transport Exon-exon Junction Complex Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Translation Cellular Localization Post-transcriptional Regulation Of Gene Expression Intracellular Transport Transcription Export Complex Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Establishment Of Localization In Cell Telomeric DNA Binding RNA Catabolic Process Response To Cytokine Response To Peptide Negative Regulation Of Gene Expression Neuron Projection Organization Regulation Of Long-term Synaptic Potentiation Peptidyl-serine Phosphorylation MRNA Metabolic Process Negative Regulation Of Protein Localization To Nucleus MRNA Binding Cellular Response To Amyloid-beta Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Response To Amyloid-beta Positive Regulation Of Toll Signaling Pathway Regulation Of Microtubule Anchoring At Centrosome Glial Cell Development Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Neuron Apoptotic Process Regulation Of Protein Metabolic Process Protein Phosphorylation Nucleobase-containing Compound Catabolic Process RNA Binding Acetylcholine Receptor Activator Activity Response To Interleukin-1 Macromolecule Metabolic Process Lipoprotein Particle Positive Regulation Of Protein Import Phosphorylation	GPI-anchor Transamidase Activity GPI-anchor Transamidase Complex GPI Anchored Protein Biosynthesis Attachment Of GPI Anchor To Protein GPI Anchor Binding GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Glycolipid Biosynthetic Process Glycolipid Metabolic Process Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Metabolic Process Glycerophospholipid Biosynthetic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Positive Regulation Of MRNA Cis Splicing, Via Spliceosome Protein Maturation Glycerolipid Metabolic Process Phospholipid Metabolic Process Protein Retention In ER Lumen Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maintenance Of Protein Localization In Endoplasmic Reticulum Carbohydrate Derivative Biosynthetic Process Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Lipid Biosynthetic Process Organophosphate Biosynthetic Process Exon-exon Junction Complex Telomeric DNA Binding Positive Regulation Of MRNA Splicing, Via Spliceosome Carbohydrate Derivative Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maintenance Of Protein Localization In Organelle Positive Regulation Of RNA Splicing Organophosphate Metabolic Process Maintenance Of Protein Location In Cell Maintenance Of Protein Location Endoplasmic Reticulum Membrane Lipid Metabolic Process Maintenance Of Location In Cell Negative Regulation Of MRNA Catabolic Process Maintenance Of Location
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