UPF3A and PIGT

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		UPF3A	PIGT
Gene Name		UPF3 regulator of nonsense transcripts homolog A (yeast)	phosphatidylinositol glycan anchor biosynthesis, class T
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Exon-exon Junction Complex Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Membrane Membrane Cytoplasmic Membrane-bounded Vesicle Integral Component Of Endoplasmic Reticulum Membrane GPI-anchor Transamidase Complex
	Molecular Function	Nucleotide Binding RNA Binding Nucleocytoplasmic Transporter Activity Protein Binding	GPI-anchor Transamidase Activity Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nucleocytoplasmic Transport Gene Expression Positive Regulation Of Translation MRNA Transport	C-terminal Protein Lipidation Attachment Of GPI Anchor To Protein Neuron Differentiation Post-translational Protein Modification Cellular Protein Metabolic Process Neuron Apoptotic Process
Pathways		Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Post-translational protein modification Attachment of GPI anchor to uPAR Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ALYREF APP GSK3B IFITM2 NXF1 PIGT RBM8A SMG1 UPF1	3 interactors: GPAA1 PIGK UPF3A
Entrez ID		65110	51604
HPRD ID		09274	15136
Ensembl ID		ENSG00000169062	ENSG00000124155
Uniprot IDs		B3KUE7 Q9H1J1	B7Z1N3 Q969N2
PDB IDs		2L08
Enriched GO Terms of Interacting Partners?		Nuclear Export MRNA Export From Nucleus RNA Export From Nucleus Nucleocytoplasmic Transport Nuclear Transport MRNA Transport RNA Transport RNA Localization Cytoplasmic Transport Intracellular Transport MRNA Metabolic Process Establishment Of Localization In Cell MRNA 3'-end Processing Cellular Localization Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Termination Of RNA Polymerase II Transcription Regulation Of Translation Neuron Apoptotic Process Neuron Death DNA-templated Transcription, Termination Transport MRNA Processing Aromatic Compound Catabolic Process Response To Stress Gene Expression Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Type B Pancreatic Cell Development Synaptic Growth At Neuromuscular Junction Superior Temporal Gyrus Development Peptidyl-serine Phosphorylation RNA Processing Re-entry Into Mitotic Cell Cycle Collateral Sprouting In Absence Of Injury Negative Regulation Of Neuron Maturation Regulation Of Protein Binding Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Cellular Response To Stress Collateral Sprouting Axon Midline Choice Point Recognition Cellular Response To Interleukin-3 Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Neuron Differentiation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Glycogen (starch) Synthase Activity Axon Choice Point Recognition	Attachment Of GPI Anchor To Protein C-terminal Protein Lipidation GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process Post-translational Protein Modification Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Protein Retention In ER Lumen Maintenance Of Protein Localization In Endoplasmic Reticulum Lipid Biosynthetic Process Cellular Lipid Metabolic Process Organophosphate Metabolic Process Lipid Metabolic Process Positive Regulation Of Translation Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Transport
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