RBM8A and DPH1

Number of citations of the paper that reports this interaction (PMID 11013075)
6

Data Source:
HPRD (two hybrid)

		RBM8A	DPH1
Gene Name		RNA binding motif protein 8A	diphthamide biosynthesis 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome	Nucleus Cytosol
	Molecular Function	Nucleotide Binding RNA Binding MRNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus Regulation Of Translation RNA Splicing Gene Expression MRNA 3'-end Processing	Cell Proliferation Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing	Synthesis of diphthamide-EEF2 Post-translational protein modification Gamma carboxylation, hypusine formation and arylsulfatase activation
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: APP DPH1 EIF4A3 FBXO25 IKBKG IPO13 MAGOH MAGOHB MCM7 NXF1 RNPS1 SF3B2 SRPK1 SRPK2 TOE1 UPF3A UPF3B	3 interactors: HSPA5 RBM8A TFCP2
Entrez ID		9939	1801
HPRD ID		05609	04634
Ensembl ID		ENSG00000131795	ENSG00000108963
Uniprot IDs		Q9Y5S9	B3KQW7 Q9BZG8
PDB IDs		1P27 2HYI 2J0Q 2J0S 2XB2 3EX7
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Transport MRNA Processing RNA Transport RNA Localization RNA Splicing RNA Processing MRNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA 3'-end Processing Nucleocytoplasmic Transport Nuclear Transport Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process MRNA Export From Nucleus Gene Expression RNA Catabolic Process Regulation Of MRNA Splicing, Via Spliceosome RNA Export From Nucleus Regulation Of MRNA Processing Regulation Of RNA Splicing RNA Metabolic Process Regulation Of Translation Nuclear Export Nucleobase-containing Compound Metabolic Process Termination Of RNA Polymerase II Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cytoplasmic Transport Cellular Nitrogen Compound Metabolic Process Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression DNA-templated Transcription, Termination Positive Regulation Of Translation Nitrogen Compound Metabolic Process Establishment Of Localization In Cell Intracellular Transport Cellular Localization Positive Regulation Of Viral Genome Replication Regulation Of Alternative MRNA Splicing, Via Spliceosome Cellular Macromolecule Catabolic Process Cellular Metabolic Process Positive Regulation Of Gene Expression Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Viral Process Negative Regulation Of Viral Genome Replication Positive Regulation Of Cellular Protein Metabolic Process Nuclear Speck Organization	Regulation Of Protein Folding In Endoplasmic Reticulum Cerebellum Structural Organization ER Overload Response Maintenance Of Protein Localization In Endoplasmic Reticulum
Tagcloud ?		appearance bodies casc3 core correlate correlates cytoplasm cytoplasmic deregulation determining disassembly eif4aiii ejc exon fate foci granules junction loaded localizes magoh mln51 movements onto overexpressed overexpressing spliced unlike y14	17p13 ablation biosynthesis cleft conditional cranial craniofacial crest dieker diphthamide diphtheria dispensable embryos jaw lethality mammals mandible mesoderm mesodermal miller neural null ovca1 palate paraxial perinatal rescue shortened tagged
Tagcloud (Difference) ?		appearance bodies casc3 core correlate correlates cytoplasm cytoplasmic deregulation determining disassembly eif4aiii ejc exon fate foci granules junction loaded localizes magoh mln51 movements onto overexpressed overexpressing spliced unlike y14	17p13 ablation biosynthesis cleft conditional cranial craniofacial crest dieker diphthamide diphtheria dispensable embryos jaw lethality mammals mandible mesoderm mesodermal miller neural null ovca1 palate paraxial perinatal rescue shortened tagged
Tagcloud (Intersection) ?