SPOCK2 and PLXNB3

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		SPOCK2	PLXNB3
Gene Name		sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	plexin B3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix	Intracellular Plasma Membrane Integral Component Of Membrane
	Molecular Function	Calcium Ion Binding Glycosaminoglycan Binding Extracellular Matrix Binding	Protein Binding Semaphorin Receptor Activity Protein Domain Specific Binding Rho GDP-dissociation Inhibitor Binding
	Biological Process	Signal Transduction Synapse Assembly Positive Regulation Of Cell-substrate Adhesion Peptide Cross-linking Via Chondroitin 4-sulfate Glycosaminoglycan Extracellular Matrix Organization Regulation Of Cell Differentiation	Positive Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cell Adhesion Axon Guidance Negative Regulation Of Lamellipodium Assembly Negative Regulation Of Cell Migration Negative Regulation Of GTPase Activity Positive Chemotaxis Cell Chemotaxis Semaphorin-plexin Signaling Pathway
Pathways			Axon guidance Semaphorin interactions Other semaphorin interactions
Drugs
Diseases
GWAS		Insulin-like growth factors ( 21216879) Smoking behavior ( 22832964)
Protein-Protein Interactions		3 interactors: PLXNB3 SPOCK3 TES	8 interactors: ARHGEF11 BTBD3 CUL7 CUL9 MAGI2 MAGI3 RIT2 SPOCK2
Entrez ID		9806	5365
HPRD ID		12146	02198
Ensembl ID		ENSG00000107742	ENSG00000198753
Uniprot IDs		Q92563	A8K920 B7Z3H9 Q9ULL4
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Lamellipodium Assembly Negative Regulation Of Hydrolase Activity Peptide Cross-linking Via Chondroitin 4-sulfate Glycosaminoglycan	Neurotrophin Signaling Pathway Nervous System Development Cytokinesis Planar Cell Polarity Pathway Involved In Axis Elongation Regulation Of Mitotic Nuclear Division Cellular Response To Growth Factor Stimulus Response To Growth Factor Positive Regulation Of Catalytic Activity Generation Of Neurons Neurogenesis Cell Morphogenesis Involved In Differentiation Cell Development Cellular Response To Organic Substance Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Regulation Of Cellular Component Organization Positive Regulation Of Neuron Projection Development Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cell Cycle Regulation Of Cell Division Negative Regulation Of Activin Receptor Signaling Pathway Signaling Glomerular Visceral Epithelial Cell Development Cell Communication Positive Regulation Of Cell Projection Organization Positive Regulation Of Hydrolase Activity Cell Cycle Process Cell Morphogenesis Positive Regulation Of Phosphoprotein Phosphatase Activity Nerve Growth Factor Signaling Pathway Peptide Cross-linking Via Chondroitin 4-sulfate Glycosaminoglycan Cytoskeleton Organization Regulation Of Catalytic Activity Positive Regulation Of Neuron Differentiation Anatomical Structure Morphogenesis Mitotic Cell Cycle Arrest Glomerular Visceral Epithelial Cell Differentiation System Development Response To Organic Substance Positive Regulation Of Receptor Internalization Positive Regulation Of Cellular Metabolic Process Regulation Of Neuron Projection Development Wnt Signaling Pathway, Planar Cell Polarity Pathway Cellular Response To Stimulus Regulation Of Activin Receptor Signaling Pathway Regulation Of Mitotic Cell Cycle Positive Regulation Of Neurogenesis Cell Cycle Cell Division Microtubule Cytoskeleton Organization
Tagcloud ?		adrenal agtrap alpha1 apelin apln covers ephx2 epoxide genesis gja1 glands hydrolase hypertensive isolating kynu kynureninase kyoto normotensive osteonectin prone rgs2 rising shr shrsp sparc substrains urotensin uts2 wky	alias amplifications bgn casp9 ccnc cgh e2f5 eck efnb3 epha2 ercc1 fgf3 fgr frap1 hspg2 il12a l1cam lamc1 mexican nonaffected outline pctk2 pctk3 plexr tnfrsf10a tnfrsf10b tp73 turned underexpressed
Tagcloud (Difference) ?		adrenal agtrap alpha1 apelin apln covers ephx2 epoxide genesis gja1 glands hydrolase hypertensive isolating kynu kynureninase kyoto normotensive osteonectin prone rgs2 rising shr shrsp sparc substrains urotensin uts2 wky	alias amplifications bgn casp9 ccnc cgh e2f5 eck efnb3 epha2 ercc1 fgf3 fgr frap1 hspg2 il12a l1cam lamc1 mexican nonaffected outline pctk2 pctk3 plexr tnfrsf10a tnfrsf10b tp73 turned underexpressed
Tagcloud (Intersection) ?