PLXNB3 and BTBD3

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		PLXNB3	BTBD3
Description		plexin B3	BTB domain containing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Semaphorin Receptor Complex Plasma Membrane Cell Surface Membrane	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Semaphorin Receptor Activity Protein Domain Specific Binding Rho GDP-dissociation Inhibitor Binding Cell-cell Adhesion Mediator Activity	Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Cell Adhesion Nervous System Development Synapse Assembly Regulation Of Cell Shape Negative Regulation Of Lamellipodium Assembly Positive Regulation Of Neuron Projection Development Negative Regulation Of Cell Migration Negative Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Positive Chemotaxis Cell Chemotaxis Semaphorin-plexin Signaling Pathway	Nervous System Development Cerebral Cortex Development Neurogenesis Dendrite Morphogenesis
Pathways		Other semaphorin interactions
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Benign prostatic hyperplasia ( 30988330) Cardiac hypertrophy ( 21348951) Cognitive decline rate in late mild cognitive impairment ( 26252872) Diastolic blood pressure ( 30224653) Hearing function ( 25060954) Intraocular pressure ( 29785010) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Serum metabolite levels ( 33031748) Serum metabolite ratios in chronic kidney disease ( 29545352)
Interacting Genes		10 interacting genes: ARHGEF11 BTBD3 CUL7 CUL9 DSCR9 HSPA13 MAGI2 MAGI3 RIT2 SPOCK2	10 interacting genes: BTBD6 CDC37 CUL3 GORASP2 MEOX2 PLXNB3 RNF4 SUMO1 TEPSIN UBE2I
Entrez ID		5365	22903
HPRD ID		02198	12538
Ensembl ID		ENSG00000198753	ENSG00000132640
Uniprot IDs		A8K920 Q9ULL4	B4DK27 B4DRI6 Q9Y2F9
PDB IDs
Enriched GO Terms of Interacting Partners?		Cullin-RING Ubiquitin Ligase Complex	Small Protein Activating Enzyme Binding PML Body Transcription Factor Binding Presynaptic Cytosol Postsynaptic Cytosol Roof Of Mouth Development Post-translational Protein Modification Nuclear Body Protein Modification By Small Protein Conjugation Protein Autoubiquitination Protein Sumoylation SUMO Conjugating Enzyme Activity Nuclear Pore Regulation Of Protein Stability Trophectodermal Cellular Morphogenesis Liver Morphogenesis HSP90-CDC37 Chaperone Complex Coated Vesicle Membrane Rho GDP-dissociation Inhibitor Binding Regulation Of Kinetochore Assembly Protein K48-linked Ubiquitination RING-like Zinc Finger Domain Binding Protein Localization To Nuclear Pore Regulation Protein Catabolic Process At Postsynapse
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