SPOCK2

Description		SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix
	Molecular Function	Calcium Ion Binding Protein Binding Collagen Binding Glycosaminoglycan Binding Metalloendopeptidase Inhibitor Activity Extracellular Matrix Binding
	Biological Process	Synapse Assembly Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Regulation Of Cell Differentiation Cellular Response To Leukemia Inhibitory Factor Positive Regulation Of Cell Motility
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Insulin-like growth factors ( 21216879) Response to antioxidants and zinc in age-related macular degeneration (disease progression) ( 33751636) Smoking behavior ( 22832964)
Interacting Genes		4 interacting genes: DSCR9 PLXNB3 SPOCK3 TES
Entrez ID		9806
HPRD ID		12146
Ensembl ID		ENSG00000107742
Uniprot IDs		Q92563
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Hydrolase Activity Negative Regulation Of Catalytic Activity Rho GDP-dissociation Inhibitor Binding Semaphorin Receptor Activity Semaphorin Receptor Complex Negative Regulation Of Lamellipodium Assembly Negative Regulation Of GTPase Activity Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Metalloendopeptidase Inhibitor Activity Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Regulation Of Endopeptidase Activity Glycosaminoglycan Binding Regulation Of Catalytic Activity Extracellular Matrix Binding
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