KIAA0513 and HAX1

Number of citations of the paper that reports this interaction (PMID 17010949)
2

Data Source:
HPRD (two hybrid)

		KIAA0513	HAX1
Gene Name		KIAA0513	HCLS1 associated protein X-1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nuclear Envelope Transcription Factor Complex Mitochondrion Endoplasmic Reticulum Actin Cytoskeleton Apical Plasma Membrane Sarcoplasmic Reticulum Lamellipodium Clathrin-coated Vesicle Nuclear Membrane
	Molecular Function		Protein Binding Protein Domain Specific Binding Interleukin-1 Binding Protein N-terminus Binding
	Biological Process		Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Actin Filament Polymerization Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Kinase B Signaling Cellular Response To Cytokine Stimulus Regulation Of Mitochondrion Degradation Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Actin Cytoskeleton Reorganization
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 22959728)
Protein-Protein Interactions		4 interactors: APP HAX1 INTS4 WWC1	23 interactors: ABCB1 ABCB11 ABCB4 BIRC3 CTTN DGKD EIF3F HCLS1 HNF4G IL1A KIAA0513 MAPK10 NEDD4L PKD2 POLR1D PPP3CC RBX1 RPA1 STAT5B SVIL YWHAQ ZNF420 ZNRD1
Entrez ID		9764	10456
HPRD ID		17192	12075
Ensembl ID		ENSG00000135709	ENSG00000143575
Uniprot IDs		B4DSS5 O60268	O00165
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Regulation Of Peptidyl-tyrosine Phosphorylation Collateral Sprouting In Absence Of Injury Regulation Of Protein Targeting To Mitochondrion Regulation Of Phosphorylation Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Developmental Growth Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Hippo Signaling Regulation Of Phosphorus Metabolic Process Axon Choice Point Recognition Regulation Of Hippo Signaling Positive Regulation Of Granulocyte Differentiation Neuron Remodeling Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Mitochondrion Degradation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Intracellular Transport Positive Regulation Of Actin Cytoskeleton Reorganization Regulation Of Cellular Ketone Metabolic Process Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Regulation Of Growth Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Hippo Signaling Positive Regulation Of Cellular Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity SnRNA Processing Mating Behavior Regulation Of Signal Transduction Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Negative Regulation Of Organ Growth SnRNA Metabolic Process Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Intracellular Signal Transduction Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway	Positive Regulation Of Organelle Organization Positive Regulation Of Interleukin-2 Production Xenobiotic Transport Response To Abiotic Stimulus Positive Regulation Of Transport DNA-templated Transcription, Initiation Regulation Of Protein Localization Regulation Of Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Interleukin-2 Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Signal Transduction Positive Regulation Of Cell Cycle Regulation Of Organelle Organization Intracellular Signal Transduction Regulation Of Signaling Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Interleukin-2 Biosynthetic Process Regulation Of Apoptotic Process Response To Stimulus Regulation Of Cellular Localization Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Positive Regulation Of Cytokine Production Regulation Of Establishment Of Protein Localization Transcription Initiation From RNA Polymerase I Promoter Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cell Death Drug Transmembrane Transport Positive Regulation Of Cation Channel Activity Transcription From RNA Polymerase I Promoter Immune System Process Response To Stress Regulation Of Protein Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Transporter Activity Acute-phase Response Regulation Of Intracellular Transport Positive Regulation Of Innate Immune Response Actin Filament Polymerization Protein Monoubiquitination Positive Regulation Of Intracellular Signal Transduction Drug Transport Signal Transduction Negative Regulation Of Ion Transmembrane Transport Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Ion Transmembrane Transporter Activity Metanephric Cortex Development Metanephric Cortical Collecting Duct Development JAK-STAT Cascade
Tagcloud ?			1222a abolishing aciduria arg408gly atp2a2 atrophy biochemically caseinolytic cataracts cerebellar clpb congenital deleterious disability encephalopathy exome intellectual kostmann methylglutaconic movement neutropenia nonprogressive overlapping peptidase prenatal sanger scn unrelated zebrafish
Tagcloud (Difference) ?			1222a abolishing aciduria arg408gly atp2a2 atrophy biochemically caseinolytic cataracts cerebellar clpb congenital deleterious disability encephalopathy exome intellectual kostmann methylglutaconic movement neutropenia nonprogressive overlapping peptidase prenatal sanger scn unrelated zebrafish
Tagcloud (Intersection) ?