HAX1 and ZNF420

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		HAX1	ZNF420
Gene Name		HCLS1 associated protein X-1	zinc finger protein 420
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Transcription Factor Complex Mitochondrion Endoplasmic Reticulum Actin Cytoskeleton Apical Plasma Membrane Sarcoplasmic Reticulum Lamellipodium Clathrin-coated Vesicle Nuclear Membrane	Nucleus Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding Interleukin-1 Binding Protein N-terminus Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Actin Filament Polymerization Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Kinase B Signaling Cellular Response To Cytokine Stimulus Regulation Of Mitochondrion Degradation Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Actin Cytoskeleton Reorganization	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: ABCB1 ABCB11 ABCB4 BIRC3 CTTN DGKD EIF3F HCLS1 HNF4G IL1A KIAA0513 MAPK10 NEDD4L PKD2 POLR1D PPP3CC RBX1 RPA1 STAT5B SVIL YWHAQ ZNF420 ZNRD1	8 interactors: CDC42 CDK2AP1 CYP4V2 CYP51A1 HAX1 SLC1A7 TNFRSF1B TRIM28
Entrez ID		10456	147923
HPRD ID		12075	08122
Ensembl ID		ENSG00000143575	ENSG00000197050
Uniprot IDs		O00165	Q8TAQ5
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Organelle Organization Positive Regulation Of Interleukin-2 Production Xenobiotic Transport Response To Abiotic Stimulus Positive Regulation Of Transport DNA-templated Transcription, Initiation Regulation Of Protein Localization Regulation Of Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Interleukin-2 Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Signal Transduction Positive Regulation Of Cell Cycle Regulation Of Organelle Organization Intracellular Signal Transduction Regulation Of Signaling Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Interleukin-2 Biosynthetic Process Regulation Of Apoptotic Process Response To Stimulus Regulation Of Cellular Localization Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Positive Regulation Of Cytokine Production Regulation Of Establishment Of Protein Localization Transcription Initiation From RNA Polymerase I Promoter Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cell Death Drug Transmembrane Transport Positive Regulation Of Cation Channel Activity Transcription From RNA Polymerase I Promoter Immune System Process Response To Stress Regulation Of Protein Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Transporter Activity Acute-phase Response Regulation Of Intracellular Transport Positive Regulation Of Innate Immune Response Actin Filament Polymerization Protein Monoubiquitination Positive Regulation Of Intracellular Signal Transduction Drug Transport Signal Transduction Negative Regulation Of Ion Transmembrane Transport Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Ion Transmembrane Transporter Activity Metanephric Cortex Development Metanephric Cortical Collecting Duct Development JAK-STAT Cascade	Regulation Of Intracellular Protein Transport Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Intracellular Transport Cholesterol Biosynthetic Process Via 24,25-dihydrolanosterol Positive Regulation Of Protein Metabolic Process Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Cellular Metabolic Process Negative Regulation Of DNA Demethylation Positive Regulation Of Hair Follicle Cell Proliferation Fatty Acid Omega-oxidation Regulation Of Protein Transport Actin Filament Branching Submandibular Salivary Gland Formation Positive Regulation Of DNA Metabolic Process Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Targeting To Mitochondrion Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Positive Regulation Of Protein Phosphorylation Convergent Extension Involved In Axis Elongation Regulation Of Protein Localization Establishment Of Golgi Localization Regulation Of Genetic Imprinting DNA Methylation Involved In Embryo Development Positive Regulation Of Metalloenzyme Activity Positive Regulation Of Phosphorylation Positive Regulation Of Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Intracellular Transport Neuron Fate Determination Epithelial-mesenchymal Cell Signaling Positive Regulation Of Granulocyte Differentiation Regulation Of Protein Heterodimerization Activity Regulation Of Mitochondrion Degradation Keratinocyte Development Regulation Of Synapse Structural Plasticity Regulation Of Protein Metabolic Process Regulation Of Cellular Localization Regulation Of Protein Phosphorylation Positive Regulation Of Pseudopodium Assembly Nuclear Migration RNA Destabilization Cardiac Conduction System Development Convergent Extension Positive Regulation Of Membrane Protein Ectodomain Proteolysis Golgi Localization Negative Regulation Of Viral Release From Host Cell
Tagcloud ?		1222a abolishing aciduria arg408gly atp2a2 atrophy biochemically caseinolytic cataracts cerebellar clpb congenital deleterious disability encephalopathy exome intellectual kostmann methylglutaconic movement neutropenia nonprogressive overlapping peptidase prenatal sanger scn unrelated zebrafish
Tagcloud (Difference) ?		1222a abolishing aciduria arg408gly atp2a2 atrophy biochemically caseinolytic cataracts cerebellar clpb congenital deleterious disability encephalopathy exome intellectual kostmann methylglutaconic movement neutropenia nonprogressive overlapping peptidase prenatal sanger scn unrelated zebrafish
Tagcloud (Intersection) ?