IFT140 and CELSR3

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		IFT140	CELSR3
Gene Name		intraflagellar transport 140	cadherin, EGF LAG seven-pass G-type receptor 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Axoneme Intraciliary Transport Particle A Photoreceptor Connecting Cilium Ciliary Basal Body Primary Cilium Ciliary Tip	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function	G-protein Coupled Receptor Activity Calcium Ion Binding Protein Binding
	Biological Process	Organelle Organization Intraciliary Retrograde Transport Cilium Assembly Skeletal System Morphogenesis Retina Development In Camera-type Eye Protein Localization To Cilium Renal System Development Regulation Of Cilium Assembly	Neuron Migration Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules G-protein Coupled Receptor Signaling Pathway Axonal Fasciculation Regulation Of Protein Localization Cilium Assembly
Pathways		Organelle biogenesis and maintenance Hedgehog 'off' state Signaling by Hedgehog Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CELSR3 NEK2 PFDN1 RANBP2	11 interactors: CLUH DST IFT140 SCAPER SGSM2 SPTBN2 SPTBN4 SWAP70 TRIP12 TSPYL4 UACA
Entrez ID		9742	1951
HPRD ID		11093	09179
Ensembl ID		ENSG00000187535	ENSG00000008300
Uniprot IDs		Q96RY7	Q9NYQ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Centriole-centriole Cohesion Organelle Organization Regulation Of Centriole-centriole Cohesion Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Cell Cycle Regulation Of Mitotic Centrosome Separation Protein Folding Negative Regulation Of Glucokinase Activity Organelle Assembly Centrosome Separation Mitotic Spindle Assembly Regulation Of Attachment Of Spindle Microtubules To Kinetochore Axonal Fasciculation Protein Sumoylation	Actin Filament Capping Negative Regulation Of Actin Filament Depolymerization Regulation Of Organelle Organization Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Polymerization Negative Regulation Of Protein Complex Disassembly Regulation Of Protein Depolymerization Regulation Of Protein Complex Disassembly Negative Regulation Of Histone H2A K63-linked Ubiquitination Late Endosome To Golgi Transport Negative Regulation Of Protein Complex Assembly Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Intracellular Distribution Of Mitochondria Negative Regulation Of Cytoskeleton Organization Adult Behavior Movement Of Cell Or Subcellular Component Regulation Of Protein K63-linked Ubiquitination Regulation Of Actin Filament Polymerization Intraciliary Retrograde Transport Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Clustering Of Voltage-gated Sodium Channels Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Negative Regulation Of Heart Rate Cell Projection Morphogenesis Cytoskeletal Anchoring At Plasma Membrane Cell Part Morphogenesis Neuronal Ion Channel Clustering Maintenance Of Cell Polarity Hemidesmosome Assembly Organelle Organization Cellular Component Assembly Protein Localization To Cilium Regulation Of Cellular Component Organization Mitochondrion Distribution
Tagcloud ?			avulsed avulsion biceps bpi brachial brachii c5 c7 corticospinal cst elbow electromyogram emg emx1 flexion fostering hamper innervation mbp motoneuron myelin nerves neuromuscular nmj nmjs plexus remyelination sheaths tore
Tagcloud (Difference) ?			avulsed avulsion biceps bpi brachial brachii c5 c7 corticospinal cst elbow electromyogram emg emx1 flexion fostering hamper innervation mbp motoneuron myelin nerves neuromuscular nmj nmjs plexus remyelination sheaths tore
Tagcloud (Intersection) ?