IQCB1 and CALML3

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		IQCB1	CALML3
Name		IQ motif containing B1	calmodulin like 3
Structure		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Photoreceptor Connecting Cilium Extracellular Exosome	Cytoplasm Centrosome Synaptic Vesicle Membrane Myelin Sheath Extracellular Exosome
	Molecular Function	Protein Binding Calmodulin Binding Enzyme Binding Protein-macromolecule Adaptor Activity BBSome Binding	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Cell Projection Organization Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Cilium Assembly Cytosolic Ciliogenesis	Detection Of Calcium Ion Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Calcineurin-mediated Signaling
Pathways		Anchoring of the basal body to the plasma membrane	None
Diseases		Senior-Loken syndrome	None
GWAS		Hemoglobin levels ( 32327693 ) Multiple sclerosis ( 24076602 31604244 ) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376 )	Fasting insulin ( 34074324 )
Interacting Genes		12 interacting genes: CALM2 CALML3 KIF9 LDOC1 MARCHF7 MNS1 PCMT1 PDE9A SESTD1 SMARCD1 SPG21 TRIM32	9 interacting genes: BHLHE40 C11orf65 IQCB1 IQCN ISOC2 MAPK4 MFHAS1 MYO10 TERF2IP
Entrez ID		9657	810
HPRD ID		11049	00244
Ensembl ID		ENSG00000173226	ENSG00000178363
Uniprot IDs		Q15051	P27482
PDB IDs		Not available	1GGZ
GO Terms Enriched among Interactors		Detection Of Calcium Ion Regulation Of Cilium Assembly Regulation Of Organelle Assembly Calcium Channel Complex Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Calcium Ion Transmembrane Transport Calcineurin-mediated Signaling Myelin Sheath Negative Regulation Of Cell Population Proliferation Regulation Of Organelle Organization Thyrotropin-releasing Hormone Activity Positive Regulation Of Interleukin-17-mediated Signaling Pathway Negative Regulation Of Cilium Assembly Actin Ubiquitination Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production	None