IQCB1 and LMOD1

		IQCB1	LMOD1
Description		IQ motif containing B1	leiomodin 1
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Photoreceptor Connecting Cilium Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Striated Muscle Thin Filament Actin Filament Membrane Myofibril Sarcomere
	Molecular Function	Protein Binding Calmodulin Binding Enzyme Binding Protein-macromolecule Adaptor Activity BBSome Binding	Actin Binding Tropomyosin Binding
	Biological Process	Cell Projection Organization Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Cilium Assembly Cytosolic Ciliogenesis	Muscle Contraction Actin Filament Organization Myofibril Assembly Positive Regulation Of Actin Filament Polymerization Actin Nucleation Pointed-end Actin Filament Capping
Pathways		Anchoring of the basal body to the plasma membrane	Smooth Muscle Contraction
Drugs
Diseases		Senior-Loken syndrome
GWAS		Hemoglobin levels ( 32327693) Multiple sclerosis ( 24076602 31604244) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376)	Appendicular lean mass ( 33097823) Body mass index ( 28448500 28892062 29273807) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Breast size ( 27182965) Coronary artery disease ( 29212778 33020668) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Lung function (FEV1/FVC) ( 30804560) Sleep duration (short sleep) ( 30846698)
Interacting Genes		12 interacting genes: CALM2 CALML3 KIF9 LDOC1 MARCHF7 MNS1 PCMT1 PDE9A SESTD1 SMARCD1 SPG21 TRIM32	1 interacting genes: ACTB
Entrez ID		9657	25802
HPRD ID		11049	04093
Ensembl ID		ENSG00000173226	ENSG00000163431
Uniprot IDs		Q15051	P29536
PDB IDs			4Z79 4Z8G 4Z94
Enriched GO Terms of Interacting Partners?		Detection Of Calcium Ion Regulation Of Cilium Assembly Regulation Of Organelle Assembly Calcium Channel Complex Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Calcium Ion Transmembrane Transport Calcineurin-mediated Signaling Myelin Sheath Negative Regulation Of Cell Population Proliferation Regulation Of Organelle Organization Thyrotropin-releasing Hormone Activity Positive Regulation Of Interleukin-17-mediated Signaling Pathway Negative Regulation Of Cilium Assembly Actin Ubiquitination Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production	Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Regulation Of Norepinephrine Uptake BBSome Binding Regulation Of Transepithelial Transport Protein Localization To Adherens Junction Dense Body Transporter Regulator Activity Morphogenesis Of A Polarized Epithelium Maintenance Of Animal Organ Identity Cytosolic Ciliogenesis Structural Constituent Of Postsynaptic Actin Cytoskeleton Nitric-oxide Synthase Regulator Activity BBAF Complex Tat Protein Binding Postsynaptic Actin Cytoskeleton Brahma Complex Nitric-oxide Synthase Binding NBAF Complex Apical Protein Localization RSC-type Complex Adherens Junction Assembly Negative Regulation Of Cell Differentiation Postsynaptic Actin Cytoskeleton Organization NpBAF Complex GBAF Complex Protein Localization To Cell-cell Junction Calyx Of Held Postsynaptic Cytoskeleton Organization Regulation Of Synaptic Vesicle Endocytosis Regulation Of Nucleotide-excision Repair Negative Regulation Of Developmental Process Apical Junction Complex Cortical Cytoskeleton NuA4 Histone Acetyltransferase Complex Regulation Of Synaptic Vesicle Recycling SWI/SNF Complex Maintenance Of Blood-brain Barrier Cell Projection Organization Regulation Of G0 To G1 Transition Tight Junction Nucleosomal DNA Binding Photoreceptor Cell Maintenance Kinesin Binding Substantia Nigra Development Tau Protein Binding Photoreceptor Connecting Cilium Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Myoblast Differentiation Platelet Aggregation
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