CALML3 and IQCN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		CALML3	IQCN
Description		calmodulin like 3	IQ motif containing N
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Synaptic Vesicle Membrane Myelin Sheath Extracellular Exosome	Nucleus Mitochondrion
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Detection Of Calcium Ion Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Calcineurin-mediated Signaling	Spermatid Development
Pathways
Drugs
Diseases
GWAS		Fasting insulin ( 34074324)	Visceral adipose tissue volume ( 34128465)
Interacting Genes		9 interacting genes: BHLHE40 C11orf65 IQCB1 IQCN ISOC2 MAPK4 MFHAS1 MYO10 TERF2IP	14 interacting genes: CALM1 CALM2 CALM3 CALML3 CYSRT1 LINC00839 LZTS2 MID2 PLSCR1 PUF60 RBM17 SIAH1 TRIM27 TRIP6
Entrez ID		810	80726
HPRD ID		00244	13882
Ensembl ID		ENSG00000178363	ENSG00000130518
Uniprot IDs		P27482	A0JP07 Q9H0B3
PDB IDs		1GGZ
Enriched GO Terms of Interacting Partners?			Detection Of Calcium Ion Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Calcineurin-mediated Signaling Myelin Sheath Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Titin Binding Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Calyx Of Held Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Transporter Activity Calcium Channel Complex Presynaptic Cytosol Detection Of Chemical Stimulus Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Sequestering Of Calcium Ion Negative Regulation Of Calcium Ion Transmembrane Transport Synaptic Vesicle Membrane Response To Calcium Ion Presynaptic Endocytosis Spindle Microtubule Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Substantia Nigra Development Regulation Of Calcium Ion Transmembrane Transport Response To Metal Ion Calcium Channel Regulator Activity Sperm Midpiece Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Calcium-mediated Signaling Negative Regulation Of Calcium Ion Transport G2/M Transition Of Mitotic Cell Cycle Long-term Synaptic Potentiation Positive Regulation Of Sequestering Of Calcium Ion Vesicle Sarcomere Cell Cycle G2/M Phase Transition Negative Regulation Of Voltage-gated Calcium Channel Activity Neural Nucleus Development Negative Regulation Of Cation Transmembrane Transport Protein Serine/threonine Kinase Activator Activity Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Calcium Ion Transport
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