IQCB1

Name	IQ motif containing B1
Structure	No pdb structure
Novel Interactors	6 novel interactors: CD80 LMOD1 NECTIN3 TBL1X TRH UPK1B
Interactors	12 interactors: CALM2 CALML3 KIF9 LDOC1 MARCHF7 MNS1 PCMT1 PDE9A SESTD1 SMARCD1 SPG21 TRIM32
GO Annotations	Cellular Component	Photoreceptor Outer Segment Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Photoreceptor Connecting Cilium Extracellular Exosome
	Molecular Function	Protein Binding Calmodulin Binding Enzyme Binding Protein-macromolecule Adaptor Activity BBSome Binding
	Biological Process	Cell Projection Organization Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Cilium Assembly Cytosolic Ciliogenesis
Pathways	Anchoring of the basal body to the plasma membrane
Diseases	Senior-Loken syndrome
GWAS	Hemoglobin levels ( 32327693 ) Multiple sclerosis ( 24076602 31604244 ) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376 )
Entrez ID	9657
HPRD ID	11049
Ensembl ID	ENSG00000173226
Uniprot IDs	Q15051
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Detection Of Calcium Ion Regulation Of Cilium Assembly Regulation Of Organelle Assembly Calcium Channel Complex Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Calcium Ion Transmembrane Transport Calcineurin-mediated Signaling Myelin Sheath Negative Regulation Of Cell Population Proliferation Regulation Of Organelle Organization Thyrotropin-releasing Hormone Activity Positive Regulation Of Interleukin-17-mediated Signaling Pathway Negative Regulation Of Cilium Assembly Actin Ubiquitination Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production