CALML3 and ISOC2

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		CALML3	ISOC2
Description		calmodulin like 3	isochorismatase domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Synaptic Vesicle Membrane Myelin Sheath Extracellular Exosome	Nucleus Cytoplasm Mitochondrion
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Detection Of Calcium Ion Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Calcineurin-mediated Signaling	Protein Destabilization
Pathways
Drugs
Diseases
GWAS		Fasting insulin ( 34074324)
Interacting Genes		9 interacting genes: BHLHE40 C11orf65 IQCB1 IQCN ISOC2 MAPK4 MFHAS1 MYO10 TERF2IP	5 interacting genes: APP CALML3 CDKN2A LSM8 PDK2
Entrez ID		810	79763
HPRD ID		00244	08030
Ensembl ID		ENSG00000178363	ENSG00000063241
Uniprot IDs		P27482	Q96AB3
PDB IDs		1GGZ
Enriched GO Terms of Interacting Partners?			Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Phosphorus Metabolic Process Growth Cone Lamellipodium Regulation Of Calcium Ion Transmembrane Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Intracellular Signal Transduction Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Calcium-mediated Signaling Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Amyloid Fibril Formation Regulation Of Calcium-mediated Signaling Lipoprotein Particle Regulation Of Protein Localization To Nucleus Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Response To Reactive Oxygen Species Negative Regulation Of Protein Neddylation Ubiquitin-protein Transferase Inhibitor Activity Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Senescence-associated Heterochromatin Focus Ligase Inhibitor Activity Negative Regulation Of Immature T Cell Proliferation In Thymus Apoptotic Process Involved In Mammary Gland Involution Cellular Response To Reactive Oxygen Species Pyruvate Dehydrogenase (acetyl-transferring) Kinase Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway
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