KRTAP13-1 and TBC1D10C

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KRTAP13-1	TBC1D10C
Description		keratin associated protein 13-1	TBC1 domain family member 10C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Cytosol Plasma Membrane Membrane Filopodium Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Structural Molecule Activity	GTPase Activator Activity Protein Binding
	Biological Process		Calcineurin-NFAT Signaling Cascade B Cell Activation Retrograde Transport, Endosome To Golgi Negative Regulation Of B Cell Activation ERK1 And ERK2 Cascade Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Cilium Assembly
Pathways		Keratinization	Neutrophil degranulation TBC/RABGAPs
Drugs
Diseases
GWAS		Treatment resistant depression ( 30468137)	Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)
Interacting Genes		43 interacting genes: ARMC7 ATXN1L BAG4 BANF2 BCL6 CFAP206 CHRD COL8A1 CRACR2A FAM221B GLRX3 KLHL38 KRT34 KRTAP10-3 KRTAP10-5 KRTAP12-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LONRF1 MAPKBP1 MEIS2 NEK6 NMUR2 NOXA1 OTX1 PITX1 POU4F2 PROP1 PRR13 PSPC1 RANBP3 RBPMS RIN1 SCAMP1 STK16 TBC1D10C TBX6 TEKT4 TNS2 UBQLN2 VENTX YTHDF1	7 interacting genes: APP HOXA1 KLHL12 KRTAP13-1 KRTAP5-9 NOTCH2NLA PPP3R2
Entrez ID		140258	374403
HPRD ID		10570	13330
Ensembl ID		ENSG00000198390	ENSG00000175463
Uniprot IDs		Q8IUC0	Q8IV04
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Regulation Of Calcium Ion Transmembrane Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Visual Behavior Regulation Of Response To Calcium Ion Positive Regulation Of Calcium-mediated Signaling Calcium-mediated Signaling Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Calcium-mediated Signaling Lipoprotein Particle Growth Factor Receptor Binding Main Axon Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Semicircular Canal Formation Abducens Nerve Formation Optokinetic Behavior Intermediate Filament Sperm Mitochondrial Sheath Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Negative Regulation Of Calcium Ion Import Across Plasma Membrane Calcineurin Complex Axon Choice Point Recognition Identical Protein Binding Heparan Sulfate Binding Signaling Receptor Activator Activity Embryonic Neurocranium Morphogenesis
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