ATP6V1G1 and ATP6V1E1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (biochemical)
HPRD (two hybrid)

		ATP6V1G1	ATP6V1E1
Gene Name		ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Cytosol Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Extracellular Vesicular Exosome	Mitochondrion Lysosomal Membrane Endosome Cytosol Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting Two-sector ATPase Complex, Catalytic Domain Extracellular Vesicular Exosome
	Molecular Function	Hydrogen-exporting ATPase Activity, Phosphorylative Mechanism ATPase Binding	Protein Binding Hydrogen-exporting ATPase Activity, Phosphorylative Mechanism Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway Transferrin Transport Interaction With Host Transmembrane Transport Phagosome Maturation Hydrogen Ion Transmembrane Transport	Cellular Iron Ion Homeostasis Metabolic Process Insulin Receptor Signaling Pathway ATP Hydrolysis Coupled Proton Transport Proton Transport Transferrin Transport Interaction With Host Transmembrane Transport Phagosome Maturation
Pathways		Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor	Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AP2B1 APP ATP6V1E1 ATP6V1E2 BCL2L11 GOLGA2 LDOC1 MAGEA6	13 interactors: ALDOA ALDOB ALDOC APP ATP6V0E1 ATP6V1G1 ATP6V1G2 ATP6V1H MESDC2 SLC9A3R1 SOS1 TRAF6 XRCC6
Entrez ID		9550	529
HPRD ID		06294	00163
Ensembl ID			ENSG00000131100
Uniprot IDs		O75348	P36543 Q53Y06
PDB IDs
Enriched GO Terms of Interacting Partners?		Interaction With Host Transition Metal Ion Homeostasis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Transferrin Transport Phagosome Maturation Enzyme Linked Receptor Protein Signaling Pathway ATP Hydrolysis Coupled Proton Transport Cellular Metal Ion Homeostasis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Iron Ion Transport Cellular Cation Homeostasis Cellular Iron Ion Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Cellular Chemical Homeostasis Homeostatic Process Synaptic Growth At Neuromuscular Junction Ion Homeostasis Iron Ion Homeostasis Collateral Sprouting In Absence Of Injury Positive Regulation Of Peptidase Activity Regulation Of Protein Binding Insulin Receptor Signaling Pathway Cellular Homeostasis Apoptotic Process Involved In Embryonic Digit Morphogenesis Positive Regulation Of Apoptotic Process By Virus Cell Surface Receptor Signaling Pathway Hydrogen Ion Transmembrane Transport Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Fibroblast Apoptotic Process Cellular Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Axon Choice Point Recognition Thymocyte Apoptotic Process B Cell Apoptotic Process Post-embryonic Organ Morphogenesis Chemical Homeostasis Proton Transport Neurotrophin Signaling Pathway Positive Regulation Of Killing Of Cells Of Other Organism Regulation Of Killing Of Cells Of Other Organism Cellular Process Regulating Host Cell Cycle In Response To Virus Neuron Remodeling Positive Regulation Of Protein Homooligomerization Regulation Of Binding Positive Regulation Of Cell Cycle	Fructose 1,6-bisphosphate Metabolic Process Transferrin Transport Homeostatic Process Phagosome Maturation Transition Metal Ion Homeostasis Insulin Receptor Signaling Pathway Cellular Homeostasis Cellular Response To Insulin Stimulus Cellular Ion Homeostasis Iron Ion Transport Cellular Iron Ion Homeostasis Fructose Metabolic Process Cellular Chemical Homeostasis Interaction With Host Ion Homeostasis Response To Insulin Iron Ion Homeostasis Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Metal Ion Homeostasis Hydrogen Ion Transmembrane Transport Response To Organonitrogen Compound Cellular Cation Homeostasis Response To Peptide Hormone Chemical Homeostasis Metal Ion Homeostasis Cellular Response To Organonitrogen Compound Gluconeogenesis Enzyme Linked Receptor Protein Signaling Pathway Response To Peptide Proton Transport Cell Surface Receptor Signaling Pathway Hexose Biosynthetic Process Cellular Response To Hormone Stimulus Glycolytic Process Monovalent Inorganic Cation Transport Vacuolar Acidification Response To Stimulus Pyruvate Metabolic Process Intracellular PH Reduction Metal Ion Transport Carbohydrate Catabolic Process Glucose Metabolic Process PH Reduction Carbohydrate Biosynthetic Process Response To Hormone Protein Complex Assembly Response To Organic Substance Platelet Activation
Tagcloud ?			ae2 apical aqp9 aquaporin bapta bdkrb1 bdkrb2 caput cauda ciliated colocalize corpus ducts efferent epididymal epididymidis epididymis exchanger glycerol kks lcm microdissection nonciliated official pole solute stereocilia symbol uniform
Tagcloud (Difference) ?			ae2 apical aqp9 aquaporin bapta bdkrb1 bdkrb2 caput cauda ciliated colocalize corpus ducts efferent epididymal epididymidis epididymis exchanger glycerol kks lcm microdissection nonciliated official pole solute stereocilia symbol uniform
Tagcloud (Intersection) ?