ENTPD6 and NPSR1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		ENTPD6	NPSR1
Description		ectonucleoside triphosphate diphosphohydrolase 6	neuropeptide S receptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Golgi Apparatus Plasma Membrane Cell Surface Membrane	Cytoplasm Plasma Membrane Membrane
	Molecular Function	GDP Phosphatase Activity Guanosine-5'-triphosphate,3'-diphosphate Diphosphatase Activity Hydrolase Activity Nucleoside Diphosphate Phosphatase Activity Ribonucleoside Triphosphate Phosphatase Activity CDP Phosphatase Activity UDP Phosphatase Activity IDP Phosphatase Activity	G Protein-coupled Receptor Activity Vasopressin Receptor Activity Neuropeptide Receptor Activity
	Biological Process	Response To Magnesium Ion Response To Calcium Ion	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Eating Behavior Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Righting Reflex Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Eating Behavior Negative Regulation Of Defecation
Pathways		Phosphate bond hydrolysis by NTPDase proteins	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (s) signalling events
Drugs			Halothane
Diseases
GWAS		Adult body size ( 32376654) Allergic rhinitis ( 22036096) Body mass index ( 29273807) Brain morphology (MOSTest) ( 32665545) Diisocyanate-induced asthma ( 25918132)	Anti-chlamydia trachomatis IgG seropositivity ( 29967566) Asthma ( 29273806) Leisure-time exercise behaviour ( 30102679) Plasma anti-thyroglobulin levels ( 29678681) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		3 interacting genes: ATXN1 GSK3B NPSR1	16 interacting genes: ATP5F1A CCT2 ENTPD6 GABARAPL2 HLA-C IPO13 PGM2L1 PMPCB PRR36 RABGGTB SLC3A2 SLC41A3 SLC75A1 TERF2IP TMED10 TMEM101
Entrez ID		955	387129
HPRD ID		16013	10547
Ensembl ID		ENSG00000197586	ENSG00000187258
Uniprot IDs		B4DDM7 B4DHS2 B4DU64 B4E1D1 O75354 Q5QPI9	A0A090N8Z1 Q6W5P4
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Postsynaptic Membrane Potential Regulation Of Microtubule Anchoring At Centrosome Excitatory Postsynaptic Potential Negative Regulation Of Defecation Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Postsynapse Negative Regulation Of TORC2 Signaling Negative Regulation Of Dopaminergic Neuron Differentiation Regulation Of Glycogen (starch) Synthase Activity POZ Domain Binding Negative Regulation Of Eating Behavior Beta-catenin Destruction Complex Negative Regulation Of Glycogen Biosynthetic Process Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway ER Overload Response Regulation Of Membrane Potential Regulation Of Protein Localization To Cilium Regulation Of Dopaminergic Neuron Differentiation Regulation Of Type B Pancreatic Cell Development Regulation Of Protein Localization To Centrosome Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Protein Localization To Cilium Positive Regulation Of Protein Binding Regulation Of Mesenchymal Stem Cell Differentiation Cellular Response To Interleukin-3 Positive Regulation Of Protein Localization To Centrosome Poly(G) Binding Nuclear Inclusion Body Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Righting Reflex Negative Regulation Of Feeding Behavior Regulation Of Eating Behavior Vasopressin Receptor Activity TORC2 Signaling Negative Regulation Of Calcineurin-NFAT Signaling Cascade Wnt Signalosome Regulation Of Cellular Response To Heat Maintenance Of Cell Polarity Regulation Of TORC2 Signaling Protein Kinase A Catalytic Subunit Binding Dynactin Binding Reflex Negative Regulation Of Calcium-mediated Signaling Tau-protein Kinase Activity Positive Regulation Of Protein Export From Nucleus Neuropeptide Receptor Activity	Mitochondrial Processing Peptidase Complex Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Protein Processing Adenyl Ribonucleotide Binding Transmembrane Transport Guanosine-5'-triphosphate,3'-diphosphate Diphosphatase Activity Apical Pole Of Neuron Tetracycline Transmembrane Transport Tetracycline Transmembrane Transporter Activity Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Glucose-1,6-bisphosphate Synthase Activity
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