TBPL1 and NDUFA6

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TBPL1	NDUFA6
Description		TATA-box binding protein like 1	NADH:ubiquinone oxidoreductase subunit A6
Image		No pdb structure
GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Transcription Factor TFIIA Complex Cytoplasm	Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane Respiratory Chain Complex I
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity General Transcription Initiation Factor Activity	NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Acrosome Assembly DTTP Biosynthetic Process DNA-templated Transcription Initiation Transcription By RNA Polymerase II Spermatogenesis Spermatid Nucleus Differentiation Nucleobase-containing Compound Biosynthetic Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Mitochondrial Respiratory Chain Complex I Assembly Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways			Respiratory electron transport Complex I biogenesis
Drugs			NADH
Diseases
GWAS		Height ( 28552196) Night sleep phenotypes ( 27126917)	Autism spectrum disorder or schizophrenia ( 28540026) Intelligence ( 28530673) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		18 interacting genes: ABCF3 APP DVL3 FBXO7 GTF2A1 GTF2A2 GTF2B IRAK4 LSM5 NDUFA6 NF1 PLIN3 PRNP PTCD3 RAB35 RPL10 SLC35F6 TNNT1	4 interacting genes: ATP5MF BAG6 HSPB2 TBPL1
Entrez ID		9519	4700
HPRD ID		09272	11884
Ensembl ID		ENSG00000028839	ENSG00000184983
Uniprot IDs		P62380	A0A2Y9D025 P56556
PDB IDs			5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Regulation Of Long-term Synaptic Potentiation Cytosol TBP-class Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Transcription Factor TFIIA Complex Transcription Factor TFIID Complex Protein Heterodimerization Activity RNA Polymerase II Preinitiation Complex Assembly RNA Polymerase II General Transcription Initiation Factor Binding Transcription Initiation At RNA Polymerase II Promoter Transcription Preinitiation Complex Assembly Positive Regulation Of Neuron Apoptotic Process Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Negative Regulation Of Long-term Synaptic Potentiation Transcription Preinitiation Complex DNA-templated Transcription Initiation Regulation Of Neuron Apoptotic Process Intracellular Copper Ion Homeostasis Copper Ion Homeostasis RNA Polymerase II Core Promoter Sequence-specific DNA Binding Cellular Response To Copper Ion Molecular Function Activator Activity Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Postsynapse Organization Response To Copper Ion Amyloid-beta Complex Growth Cone Lamellipodium Neuron Projection Organization Regulation Of Response To Calcium Ion Response To Nerve Growth Factor Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Apoptotic Signaling Pathway Frizzled Binding Cellular Response To Nerve Growth Factor Stimulus Protein-DNA Complex Assembly Transcriptional Start Site Selection At RNA Polymerase II Promoter Positive Regulation Of Mast Cell Apoptotic Process Type 8 Metabotropic Glutamate Receptor Binding Slow-twitch Skeletal Muscle Fiber Contraction Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Negative Regulation Of Protein Localization To Nucleus Regulation Of Synaptic Plasticity Cellular Response To Amyloid-beta Protein-containing Complex Assembly Regulation Of Amyloid Precursor Protein Catabolic Process	Somatic Muscle Development Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Maintenance Of Unfolded Protein BAT3 Complex Nucleoside Triphosphate Biosynthetic Process General Transcription Initiation Factor Activity Nucleotide Biosynthetic Process DTTP Biosynthetic Process Transcription Factor TFIIA Complex Nucleoside Phosphate Biosynthetic Process Pyrimidine Deoxyribonucleotide Biosynthetic Process Internal Protein Amino Acid Acetylation Internal Peptidyl-lysine Acetylation Protein Carrier Chaperone NK T Cell Activation Spermatid Nucleus Differentiation Structural Constituent Of Eye Lens Male Gamete Generation Peptidyl-lysine Acetylation Synaptonemal Complex Assembly Spermatogenesis Proteasome Binding Positive Regulation Of ERAD Pathway Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Ubiquitin-specific Protease Binding Misfolded Protein Binding Tail-anchored Membrane Protein Insertion Into ER Membrane Deoxyribonucleotide Biosynthetic Process Nucleotide Metabolic Process 2'-deoxyribonucleotide Biosynthetic Process RNA Polymerase II Core Promoter Sequence-specific DNA Binding Carbohydrate Derivative Biosynthetic Process Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATP Synthase Complex Gamete Generation Synaptonemal Complex Organization Organophosphate Biosynthetic Process Regulation Of ERAD Pathway Nucleoside Phosphate Metabolic Process Protein Refolding Nucleobase-containing Small Molecule Metabolic Process Protein Targeting To ER Protein Insertion Into ER Membrane Acrosome Assembly Pyrimidine Nucleotide Biosynthetic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Protein Acetylation Establishment Of Protein Localization To Endoplasmic Reticulum Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Polyubiquitin Modification-dependent Protein Binding
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