NDUFA6

Description		NADH:ubiquinone oxidoreductase subunit A6
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane Respiratory Chain Complex I
	Molecular Function	NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Mitochondrial Respiratory Chain Complex I Assembly Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		Respiratory electron transport Complex I biogenesis
Drugs		NADH
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Intelligence ( 28530673) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		4 interacting genes: ATP5MF BAG6 HSPB2 TBPL1
Entrez ID		4700
HPRD ID		11884
Ensembl ID		ENSG00000184983
Uniprot IDs		A0A2Y9D025 P56556
PDB IDs		5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Somatic Muscle Development Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Maintenance Of Unfolded Protein BAT3 Complex Nucleoside Triphosphate Biosynthetic Process General Transcription Initiation Factor Activity Nucleotide Biosynthetic Process DTTP Biosynthetic Process Transcription Factor TFIIA Complex Nucleoside Phosphate Biosynthetic Process Pyrimidine Deoxyribonucleotide Biosynthetic Process Internal Protein Amino Acid Acetylation Internal Peptidyl-lysine Acetylation Protein Carrier Chaperone NK T Cell Activation Spermatid Nucleus Differentiation Structural Constituent Of Eye Lens Male Gamete Generation Peptidyl-lysine Acetylation Synaptonemal Complex Assembly Spermatogenesis Proteasome Binding Positive Regulation Of ERAD Pathway Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Ubiquitin-specific Protease Binding Misfolded Protein Binding Tail-anchored Membrane Protein Insertion Into ER Membrane Deoxyribonucleotide Biosynthetic Process Nucleotide Metabolic Process 2'-deoxyribonucleotide Biosynthetic Process RNA Polymerase II Core Promoter Sequence-specific DNA Binding Carbohydrate Derivative Biosynthetic Process Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATP Synthase Complex Gamete Generation Synaptonemal Complex Organization Organophosphate Biosynthetic Process Regulation Of ERAD Pathway Nucleoside Phosphate Metabolic Process Protein Refolding Nucleobase-containing Small Molecule Metabolic Process Protein Targeting To ER Protein Insertion Into ER Membrane Acrosome Assembly Pyrimidine Nucleotide Biosynthetic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Protein Acetylation Establishment Of Protein Localization To Endoplasmic Reticulum Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Polyubiquitin Modification-dependent Protein Binding
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