PPP1R14A and PRKD1

Number of citations of the paper that reports this interaction (PMID 15003508)
6

Data Source:
BioGRID (pull down, enzymatic study)
HPRD (in vitro, in vivo)

		PPP1R14A	PRKD1
Gene Name		protein phosphatase 1, regulatory (inhibitor) subunit 14A	protein kinase D1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleus Cytoplasm Trans-Golgi Network Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Cell Cortex
	Molecular Function	Protein Phosphatase Inhibitor Activity	Protein Serine/threonine Kinase Activity Protein Kinase C Activity Protein Binding ATP Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Phosphorylation Negative Regulation Of Catalytic Activity	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Sphingolipid Metabolic Process Apoptotic Process Inflammatory Response Golgi Organization Signal Transduction Integrin-mediated Signaling Pathway Cell Proliferation Positive Regulation Of Endothelial Cell Migration Regulation Of Keratinocyte Proliferation Positive Regulation Of Neuron Projection Development Peptidyl-serine Phosphorylation Sphingolipid Biosynthetic Process Positive Regulation Of CREB Transcription Factor Activity Positive Regulation Of Peptidyl-serine Phosphorylation Cellular Response To Oxidative Stress Intracellular Signal Transduction Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Blood Vessel Endothelial Cell Migration Small Molecule Metabolic Process Innate Immune Response Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Angiogenesis Negative Regulation Of Endocytosis Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Autophosphorylation Vascular Endothelial Growth Factor Receptor Signaling Pathway Golgi Vesicle Transport Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Cell Death Protein Kinase D Signaling Positive Regulation Of Histone Deacetylase Activity Positive Regulation Of Endothelial Cell Chemotaxis Regulation Of Integrin-mediated Signaling Pathway
Pathways			Sphingolipid metabolism Metabolism of lipids and lipoproteins Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS			Body mass index ( 23669352 20935630) Obesity-related traits ( 23251661)
Protein-Protein Interactions		15 interactors: APP CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 PRKCA PRKCE PRKCG PRKCH PRKCZ PRKD1 PRNP YWHAZ	31 interactors: ABL1 ADAP1 AKAP13 BTK C1QBP COPS2 COPS5 COPS7A EGFR EPAS1 GNB2L1 HDAC5 HDAC7 HSPB1 IBTK IGF1R JUN KIDINS220 MAPK8 MAPK9 MT2A PLCG1 PLCG2 PPP1R14A PRKCE PRKCH SRC SYK TP53 YWHAQ YWHAZ
Entrez ID		94274	5587
HPRD ID		16291	05668
Ensembl ID		ENSG00000167641	ENSG00000184304
Uniprot IDs		Q96A00	F8WBA3 Q15139
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-serine Phosphorylation Protein Phosphorylation Phosphorylation Phosphate-containing Compound Metabolic Process Platelet Activation Peptidyl-amino Acid Modification Positive Regulation Of Signal Transduction Cellular Protein Modification Process Regulation Of Cell Shape Regulation Of Cellular Component Organization Vesicle-mediated Transport Endocytosis Regulation Of Signal Transduction Blood Coagulation Hemostasis Cellular Response To Stimulus Regulation Of Signaling Signal Transduction Cell Surface Receptor Signaling Pathway Wnt Signaling Pathway Cellular Protein Metabolic Process Signaling Regulation Of Body Fluid Levels Cell Communication Wound Healing Cell Activation Positive Regulation Of Phospholipase Activity Response To Wounding Response To Stimulus Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Regulation Of Cell Morphogenesis Protein Metabolic Process Response To Stress Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cell Death Regulation Of Protein Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Wnt Signaling Pathway Regulation Of Cellular Amino Acid Metabolic Process Activation Of Phospholipase C Activity Single-organism Behavior Positive Regulation Of Phospholipase C Activity Regulation Of Phosphorylation Defense Response Regulation Of Peptidyl-tyrosine Phosphorylation Protein Autophosphorylation Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cellular Ketone Metabolic Process	Fc Receptor Signaling Pathway Cell Activation Regulation Of Phosphorylation Intracellular Signal Transduction Regulation Of Phosphorus Metabolic Process Regulation Of Signal Transduction Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Cell Death Immune Response Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Protein Phosphorylation Defense Response Enzyme Linked Receptor Protein Signaling Pathway Signaling Regulation Of Signaling Blood Coagulation Hemostasis Cell Communication Regulation Of Apoptotic Process Regulation Of Intracellular Signal Transduction Immune Response-regulating Signaling Pathway Innate Immune Response Response To Organic Substance Regulation Of Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Protein Metabolic Process Response To Wounding Cell Surface Receptor Signaling Pathway Regulation Of Catalytic Activity Positive Regulation Of Transport Apoptotic Process Cellular Response To Growth Factor Stimulus Regulation Of Body Fluid Levels Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cellular Response To Stimulus Response To Growth Factor Programmed Cell Death Wound Healing Regulation Of Protein Metabolic Process Positive Regulation Of Cell Death Cellular Response To Organic Substance Cell Death Death Regulation Of Cell Motility Positive Regulation Of Metabolic Process Positive Regulation Of Immune Response Response To Stress
Tagcloud ?			adam29 cd109 cd248 cgh chl1 cladogram crcs csmd3 ercc6 ergic3 evl fbxw7 galns gnas iranian lgr mmp2 msi msp mss p2rx7 parsimony ptprd rnf182 sfrs6 slc29a1 specifics syne1 tbx22
Tagcloud (Difference) ?			adam29 cd109 cd248 cgh chl1 cladogram crcs csmd3 ercc6 ergic3 evl fbxw7 galns gnas iranian lgr mmp2 msi msp mss p2rx7 parsimony ptprd rnf182 sfrs6 slc29a1 specifics syne1 tbx22
Tagcloud (Intersection) ?