PPP1R14A and CSNK1G3

Number of citations of the paper that reports this interaction (PubMedID 15003508)
0

Data Source:
HPRD (in vitro)

		PPP1R14A	CSNK1G3
Description		protein phosphatase 1 regulatory inhibitor subunit 14A	casein kinase 1 gamma 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Serine/threonine Phosphatase Inhibitor Activity	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Cellular Response To Xenobiotic Stimulus	Endocytosis Signal Transduction Wnt Signaling Pathway Protein Modification Process Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		RHO GTPases activate PKNs
Drugs			Purvalanol A {4-Amino-2-[(4-methoxyphenyl)amino]-1,3-thiazol-5-yl}(4-methoxyphenyl)methanone 4-Amino-2-[(3-chlorophenyl)amino]-5-(4-fluorobenzoyl)-1,3-thiazol-3-ium K-00546
Diseases
GWAS		Diverticular disease ( 30177863)	Adult asthma ( 27611488) Amyotrophic lateral sclerosis ( 19451621) Apolipoprotein B levels ( 32203549) Cholesterol, total ( 24097068) Chronotype ( 30696823) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Diastolic blood pressure ( 30578418 27618452) Heel bone mineral density ( 30598549 28869591) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 28334899 32203549) Low density lipoprotein cholesterol levels ( 32154731) Metabolite levels ( 23823483) Nickel levels ( 26025379) Pulse pressure ( 27618448) Rapid response to perioperative phenylephrine (change in systolic blood pressure) ( 33168928) Red cell distribution width ( 32888494) Systolic blood pressure ( 27618452) Total body bone mineral density ( 29304378) Total cholesterol levels ( 28334899) Virologic severity in Herpes simplex virus type 2 infection ( 29535370)
Interacting Genes		16 interacting genes: APP CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 DAPK1 PRKCA PRKCE PRKCG PRKCH PRKCZ PRKD1 PRNP YWHAZ	7 interacting genes: CLSPN DBNDD2 DRICH1 KRTAP10-10 MDFI PPP1R14A SNCA
Entrez ID		94274	1456
HPRD ID		16291	05034
Ensembl ID		ENSG00000167641	ENSG00000151292
Uniprot IDs		Q96A00	A0A8V8TKT3 Q9Y6M4
PDB IDs			2CHL 2IZR 2IZS 2IZT 2IZU 4G16 4G17 4HGL 4HGS 6GRO
Enriched GO Terms of Interacting Partners?		Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Protein Kinase Activity Kinase Activity Protein Phosphorylation Phosphorylation Diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Cell Communication Positive Regulation Of Signaling ATP Binding Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Signal Transduction Nucleotide Binding Transferase Activity Regulation Of Signal Transduction Signal Transduction Protein Modification Process Regulation Of Canonical Wnt Signaling Pathway Phosphate-containing Compound Metabolic Process Regulation Of Wnt Signaling Pathway Protein Metabolic Process Positive Regulation Of Canonical Wnt Signaling Pathway Intracellular Signal Transduction Wnt Signaling Pathway Regulation Of Protein Metabolic Process Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Catabolic Process Regulation Of Protein Localization Cytoplasm Regulation Of Proteolysis Cell Surface Receptor Signaling Pathway Positive Regulation Of Protein Localization Endocytosis Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Golgi Organization Response To Norepinephrine Cellular Response To Norepinephrine Stimulus Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Cytosol Negative Regulation Of Apoptotic Process Plasma Membrane Negative Regulation Of Programmed Cell Death Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Synaptic Transmission Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Protein Metabolic Process Import Into Cell Regulation Of Cellular Component Organization Response To Stress	Protein Sequestering Activity Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Regulation Of Phosphorus Metabolic Process Transporter Regulator Activity Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake DNA Secondary Structure Binding Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process
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