UBXN1 and TRIM39

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		UBXN1	TRIM39
Gene Name		UBX domain protein 1	tripartite motif containing 39
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Proteasome Complex Nucleus Cytoplasm Dendrite Cdc48p-Npl4p-Ufd1p AAA ATPase Complex Neuronal Cell Body	Mitochondrion Cytosol
	Molecular Function	Protein Binding Polyubiquitin Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding ATPase Binding K6-linked Polyubiquitin Binding	Protein Binding Zinc Ion Binding Ligase Activity Identical Protein Binding
	Biological Process	Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Apoptotic Process Protein Ubiquitination Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: ACVR1 BARD1 BMPR1B BRCA1 FAM189A2 HOMER2 PLA2G4A PLAA SMAD1 SMURF1 TGFBR1 TRIM39 UBE2I UBQLN1 VCP	52 interactors: APP CCNC DCUN1D1 DCX DIP2A EIF4A2 EPHB6 KDM1A LNX1 LXN MED18 MNAT1 OTUB2 OTUD6A PDLIM5 PLCD4 POLI PRPF3 PSMA6 PSMD9 RECK RNF166 SMCO3 TP53 TRIM17 TRIM21 TRIM8 TTC32 UBAC1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2N UBE2V1 UBE2W UBTD1 UBTD2 UBXN1 UBXN6 USP2 USP39 USP5 WDFY3 ZKSCAN4 ZNF26
Entrez ID		51035	56658
HPRD ID		11266	09298
Ensembl ID		ENSG00000162191	ENSG00000204599
Uniprot IDs		Q04323	Q9HCM9
PDB IDs			2DID 2DIF 2ECJ
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Process Regulation Of Cell Death BMP Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Protein Ubiquitination Protein Modification By Small Protein Conjugation Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Protein Modification Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Ossification Response To Stress Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination Protein K6-linked Ubiquitination Regulation Of Signal Transduction Positive Regulation Of Osteoblast Differentiation Signal Transduction By Phosphorylation Regulation Of Cartilage Development Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Signaling Positive Regulation Of Cell Death Positive Regulation Of Ossification Pathway-restricted SMAD Protein Phosphorylation Cellular Response To Stimulus Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cellular Protein Metabolic Process Pharyngeal System Development Regulation Of Osteoblast Differentiation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Postreplication Repair Inflammatory Response Activin Receptor Signaling Pathway Response To Organic Cyclic Compound Regulation Of Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Protein Polyubiquitination Negative Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Pattern Specification Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Cartilage Development Positive Regulation Of Bone Mineralization Cell Cycle Process Positive Regulation Of Biomineral Tissue Development Cellular Response To Growth Factor Stimulus Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation	Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Cellular Macromolecule Catabolic Process Protein Catabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Protein K11-linked Ubiquitination Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Cellular Protein Metabolic Process Proteolysis Regulation Of Ubiquitin-protein Transferase Activity Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Metabolic Process Regulation Of Proteolysis Regulation Of Protein Ubiquitination Protein K63-linked Ubiquitination Positive Regulation Of Protein Ubiquitination Regulation Of Mitotic Cell Cycle Phase Transition Toll-like Receptor 4 Signaling Pathway Regulation Of Cell Cycle Phase Transition Negative Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Toll-like Receptor Signaling Pathway Regulation Of Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cellular Response To Stress Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Cell Cycle Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Activation Of Innate Immune Response
Tagcloud ?		adaptor antiviral dengue disrupts exhibits innate interferes mavs nile oligomerization potently repressing rig rlr rlrs sendai sensed signalosome stomatitis stringently strongest tlr3 tlr4 traf3 traf6 underscore vesicular west	293t aeromonas aggregate b30 bloodthirsty btr18 btr20 btr21 btr22 danio deduced e3 gill hydrophila intestine ligase mentioned multigene nj rbcc remarkably rerio tripartite ubch6 ubiquitin ubiquitylated ubiquitylation zebrafish
Tagcloud (Difference) ?		adaptor antiviral dengue disrupts exhibits innate interferes mavs nile oligomerization potently repressing rig rlr rlrs sendai sensed signalosome stomatitis stringently strongest tlr3 tlr4 traf3 traf6 underscore vesicular west	293t aeromonas aggregate b30 bloodthirsty btr18 btr20 btr21 btr22 danio deduced e3 gill hydrophila intestine ligase mentioned multigene nj rbcc remarkably rerio tripartite ubch6 ubiquitin ubiquitylated ubiquitylation zebrafish
Tagcloud (Intersection) ?