CCDC85A and STMN2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		CCDC85A	STMN2
Gene Name		coiled-coil domain containing 85A	stathmin 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm Endosome Golgi Apparatus Membrane Lamellipodium Axon Growth Cone Vesicle Neuron Projection Neuronal Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function		Protein Binding Tubulin Binding Calcium-dependent Protein Binding
	Biological Process		Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Microtubule Polymerization Positive Regulation Of Microtubule Depolymerization Cellular Response To Nerve Growth Factor Stimulus
Pathways
Drugs
Diseases
GWAS		Menarche (age at onset) ( 21102462)	Creutzfeldt-Jakob disease ( 19081515)
Protein-Protein Interactions		3 interactors: NEK2 PFDN1 STMN2	17 interactors: CCDC85A CDK1 CEP70 EEF1A1 GPRASP1 GPRASP2 MAPK10 MAPK3 NGFR PRKACA RGS20 RGS6 SUMO1 TEX11 TFCP2 TRPC5 TXLNA
Entrez ID		114800	11075
HPRD ID		19098	09003
Ensembl ID		ENSG00000055813	ENSG00000104435
Uniprot IDs		Q96PX6	E5RGX5 Q93045
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Centriole-centriole Cohesion Negative Regulation Of Cytoskeleton Organization Regulation Of Microtubule-based Process Regulation Of Centriole-centriole Cohesion Regulation Of Mitotic Centrosome Separation Positive Regulation Of Microtubule Depolymerization Regulation Of Cytoskeleton Organization Negative Regulation Of Microtubule Polymerization Centrosome Separation Positive Regulation Of Protein Depolymerization Mitotic Spindle Assembly Regulation Of Attachment Of Spindle Microtubules To Kinetochore Cellular Response To Nerve Growth Factor Stimulus Regulation Of Microtubule Polymerization Positive Regulation Of Protein Complex Disassembly Regulation Of Organelle Organization Negative Regulation Of Microtubule Depolymerization Mitotic Spindle Organization Negative Regulation Of DNA Binding Regulation Of Centrosome Cycle Negative Regulation Of Microtubule Polymerization Or Depolymerization Cytoskeleton Organization Centrosome Cycle 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Multicellular Organismal Development Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Anatomical Structure Development Regulation Of Microtubule Polymerization Or Depolymerization Cell Cycle Mitotic Sister Chromatid Segregation Regulation Of Chromosome Segregation Spindle Assembly Regulation Of DNA Binding Sister Chromatid Segregation Negative Regulation Of Protein Polymerization Negative Regulation Of Protein Complex Disassembly Centrosome Organization Negative Regulation Of Binding Developmental Process Blastocyst Development Regulation Of Protein Depolymerization Microtubule Organizing Center Organization Cerebellum Development G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Neuron Projection Development Regulation Of Mitotic Nuclear Division Regulation Of Protein Complex Disassembly Metencephalon Development	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Nuclear Envelope Organization Neurotrophin Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Signal Transduction MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Cellular Response To Growth Factor Stimulus Activation Of Protein Kinase Activity Regulation Of Signaling Response To Growth Factor Chemotaxis Regulation Of MAP Kinase Activity Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade G2/M Transition Of Mitotic Cell Cycle Stress-activated Protein Kinase Signaling Cascade Nucleus Organization Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Axon Guidance Activation Of MAPK Activity Activation Of Innate Immune Response Innate Immune Response Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Epidermal Growth Factor Positive Regulation Of Protein Kinase Activity Positive Regulation Of Innate Immune Response Positive Regulation Of Kinase Activity Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Catalytic Activity Response To Fibroblast Growth Factor Mitotic Nuclear Envelope Disassembly Axonogenesis Positive Regulation Of MAP Kinase Activity
Tagcloud ?			bcl11a cpg f9 gab1 h3k4me3 h3k9 h3k9me3 hmgcs1 imprinting island k14ac knockout mest mobp modifications permissive rara raralpha rars recapitulated ref2l repressive rlf1 rpl39l rxralpha slc38a4 tcfap2a tex13 transcript
Tagcloud (Difference) ?			bcl11a cpg f9 gab1 h3k4me3 h3k9 h3k9me3 hmgcs1 imprinting island k14ac knockout mest mobp modifications permissive rara raralpha rars recapitulated ref2l repressive rlf1 rpl39l rxralpha slc38a4 tcfap2a tex13 transcript
Tagcloud (Intersection) ?