SELENOF and RDH11

Number of citations of the paper that reports this interaction (PubMedID 29410696)
39

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SELENOF	RDH11
Description		selenoprotein F	retinol dehydrogenase 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Photoreceptor Inner Segment Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Thioredoxin Peroxidase Activity Selenium Binding Oxidoreductase Activity	All-trans-retinol Dehydrogenase (NAD+) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Aldehyde Dehydrogenase (NADP+) Activity All-trans-retinol Dehydrogenase (NADP+) Activity 11-cis-retinol Dehydrogenase (NADP+) Activity
	Biological Process	Sperm DNA Condensation 'de Novo' Post-translational Protein Folding Cellular Oxidant Detoxification	Retinoid Metabolic Process Lipid Metabolic Process Visual Perception Retinol Metabolic Process Retinal Metabolic Process Cellular Detoxification Of Aldehyde
Pathways			The canonical retinoid cycle in rods (twilight vision) RA biosynthesis pathway Retinoid metabolism and transport
Drugs			Vitamin A
Diseases
GWAS
Interacting Genes		8 interacting genes: AGTR1 BAMBI RDH11 SEPTIN3 TUBB4A UGGT1 UGGT2 XRCC6	5 interacting genes: BLOC1S2 CA12 ROBO2 SELENOF TMEM31
Entrez ID		9403	51109
HPRD ID		09376	09707
Ensembl ID		ENSG00000183291	ENSG00000072042
Uniprot IDs		O60613	A0A0S2Z583 Q8TC12
PDB IDs
Enriched GO Terms of Interacting Partners?		UDP-glucose:glycoprotein Glucosyltransferase Activity UDP-glucosylation UDP-alpha-D-glucose Metabolic Process Endoplasmic Reticulum Mannose Trimming Protein Alpha-1,2-demannosylation Protein Deglycosylation Protein N-linked Glycosylation Via Asparagine Endoplasmic Reticulum Quality Control Compartment Nucleotide-sugar Metabolic Process Angiotensin Type I Receptor Activity Endoplasmic Reticulum-Golgi Intermediate Compartment Protein N-linked Glycosylation Bradykinin Receptor Binding Aldehyde Dehydrogenase (NADP+) Activity 11-cis-retinol Dehydrogenase (NADP+) Activity Phospholipase C-activating Angiotensin-activated Signaling Pathway Renin-angiotensin Regulation Of Aldosterone Production DNA End Binding Ku70:Ku80 Complex Unfolded Protein Binding Angiotensin Type II Receptor Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Cellular Hyperosmotic Salinity Response DNA-dependent Protein Kinase Complex Internode Region Of Axon Protein Glycosylation Glycosylation Macromolecule Glycosylation 'de Novo' Post-translational Protein Folding Hyperosmotic Salinity Response DNA-dependent Protein Kinase-DNA Ligase 4 Complex 5'-deoxyribose-5-phosphate Lyase Activity Glycosyltransferase Activity Regulation Of Renal Sodium Excretion Nonhomologous End Joining Complex Glycoprotein Biosynthetic Process Cellular Response To X-ray Nuclear Telomere Cap Complex Cellular Response To Salt Stress Protein-containing Complex Double-stranded Telomeric DNA Binding Type II Transforming Growth Factor Beta Receptor Binding All-trans-retinol Dehydrogenase (NADP+) Activity 'de Novo' Protein Folding Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Double-strand Break Repair Via Classical Nonhomologous End Joining Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of Cell Differentiation Microtubule Cytoskeleton Cellular Detoxification Of Aldehyde	Chloride Ion Homeostasis Estrous Cycle Carbonate Dehydratase Activity Ovulation Cycle Negative Regulation Of Negative Chemotaxis Olfactory Bulb Interneuron Development Endocardial Cushion Formation Apoptotic Process Involved In Luteolysis Heart Induction Axon Guidance Receptor Activity Negative Regulation Of Synapse Organization Axon Midline Choice Point Recognition Regulation Of Negative Chemotaxis Axon Choice Point Recognition Negative Regulation Of Synapse Assembly Pulmonary Valve Morphogenesis Regulation Of Heart Morphogenesis Axolemma Selenium Binding Sperm DNA Condensation 'de Novo' Post-translational Protein Folding 'de Novo' Protein Folding Thioredoxin Peroxidase Activity Anterograde Synaptic Vesicle Transport Gamma-tubulin Complex Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane Regulation Of Lysosome Size Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Regulation Of Vesicle Size BORC Complex BLOC-1 Complex Mitochondrial Outer Membrane Permeabilization Monoatomic Anion Homeostasis Retinal Ganglion Cell Axon Guidance Forebrain Neuron Development Organ Induction Platelet Dense Granule Organization Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Neuron Projection Development Outflow Tract Septum Morphogenesis Positive Regulation Of Mitochondrial Membrane Permeability
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