SEP15 and UGGT1

Number of citations of the paper that reports this interaction (PMID 11278576)
19

Data Source:
HPRD (in vitro)

		SEP15	UGGT1
Gene Name		15 kDa selenoprotein	UDP-glucose glycoprotein glucosyltransferase 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Lumen Extracellular Vesicular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Extracellular Vesicular Exosome
	Molecular Function	Selenium Binding	UDP-glucose:glycoprotein Glucosyltransferase Activity Unfolded Protein Binding
	Biological Process	'de Novo' Posttranslational Protein Folding	Protein Folding Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding UDP-glucosylation
Pathways			Diseases of glycosylation Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MOGS causes MOGS-CDG (CDG-2b) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 N-glycan trimming in the ER and Calnexin/Calreticulin cycle Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Post-translational protein modification Defective ALG3 causes ALG3-CDG (CDG-1d) Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) ER Quality Control Compartment (ERQC) Diseases associated with N-glycosylation of proteins Calnexin/calreticulin cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: BAMBI UGGT1 UGGT2 XRCC6	1 interactors: SEP15
Entrez ID		9403	56886
HPRD ID		09376	12064
Ensembl ID		ENSG00000183291	ENSG00000136731
Uniprot IDs		O60613	Q9NYU2
PDB IDs
Enriched GO Terms of Interacting Partners?		UDP-glucosylation UDP-glucose Metabolic Process Nucleotide-sugar Metabolic Process Protein N-linked Glycosylation Via Asparagine Protein N-linked Glycosylation Post-translational Protein Modification Cellular Hyperosmotic Salinity Response Protein Folding Cellular Response To X-ray Macromolecule Glycosylation Protein Glycosylation Glycosylation Establishment Of Integrated Proviral Latency Establishment Of Viral Latency Cellular Hyperosmotic Response Hyperosmotic Salinity Response Glycoprotein Biosynthetic Process Positive Regulation Of Catenin Import Into Nucleus Cellular Response To Salt Stress Glycoprotein Metabolic Process DNA Ligation Positive Regulation Of Cell Development Nucleotide Metabolic Process Double-strand Break Repair Via Nonhomologous End Joining Regulation Of Catenin Import Into Nucleus Hyperosmotic Response Nucleobase-containing Small Molecule Metabolic Process V(D)J Recombination Cellular Response To Osmotic Stress Response To X-ray Positive Regulation Of Epithelial To Mesenchymal Transition Response To Salt Stress Regulation Of Cell Development Positive Regulation Of Cell Differentiation Positive Regulation Of Stem Cell Differentiation Peptidyl-amino Acid Modification Regulation Of Epithelial To Mesenchymal Transition 'de Novo' Posttranslational Protein Folding Cellular Response To Ionizing Radiation 'de Novo' Protein Folding Organophosphate Metabolic Process Carbohydrate Metabolic Process Positive Regulation Of Protein Binding Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Macromolecule Biosynthetic Process Telomere Maintenance DNA Duplex Unwinding Macromolecule Biosynthetic Process DNA Geometric Change Positive Regulation Of Type I Interferon Production	'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Protein Folding
Tagcloud ?			aglycons analytical called chemistry correctly folded folding glucosylates glucosylating glycans glycoproteins homogeneous hydrophobic intentionally introduced isoform mannose misfolded naturally optimum performing precise recognizes sensor stemmed strengthened substrates synthetic uggt2
Tagcloud (Difference) ?			aglycons analytical called chemistry correctly folded folding glucosylates glucosylating glycans glycoproteins homogeneous hydrophobic intentionally introduced isoform mannose misfolded naturally optimum performing precise recognizes sensor stemmed strengthened substrates synthetic uggt2
Tagcloud (Intersection) ?