BTF3 and NOTO

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BTF3	NOTO
Description		basic transcription factor 3	notochord homeobox
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nascent Polypeptide-associated Complex	Chromatin Nucleus
	Molecular Function	RNA Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	In Utero Embryonic Development Protein Transport Negative Regulation Of Protein Localization To Endoplasmic Reticulum	Heart Looping Regulation Of Transcription By RNA Polymerase II Determination Of Left/right Symmetry Central Nervous System Development Brain Development Embryonic Pattern Specification Dorsal/ventral Pattern Formation Neuron Differentiation Notochord Development Motile Cilium Assembly Regulation Of Cilium Assembly
Pathways			Formation of axial mesoderm
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Monobrow thickness ( 26926045)	General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435)
Interacting Genes		12 interacting genes: APP CDC42 CEBPA CSNK2B IFTAP MED21 NMT2 NOTO POLR2B TXLNA TXLNB ZDHHC17	31 interacting genes: ANKRD11 APOBEC1 BAG3 BANP BTF3 CCDC120 CEP19 CHAF1A EIPR1 ETV3L FAM9B FOXD2 FOXH1 GLYCTK HNRNPK IP6K3 KRT34 KRTAP19-7 KRTAP5-6 KRTAP6-1 KRTAP6-3 LDLRAP1 LRP10 MAGED1 MEIS2 NKX2-4 PIH1D2 POU4F2 SBK3 TTC23 UBTFL1
Entrez ID		689	344022
HPRD ID		03966
Ensembl ID		ENSG00000145741	ENSG00000214513
Uniprot IDs		P20290	A8MTQ0
PDB IDs		3LKX 3MCB 7QWQ 7QWR 9F1B 9F1C 9F1D 9FQ0
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Response To Interleukin-1 Cell Projection Morphogenesis Growth Cone Lamellipodium Neuron Projection Organization Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Synapse Organization Regulation Of Response To Calcium Ion Amylin Binding Neuron Projection Morphogenesis Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Response To Peptide Positive Regulation Of Intracellular Signal Transduction Response To Cytokine Lipoprotein Particle Chromatin Binding Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of G Protein-coupled Receptor Internalization Macrophage Differentiation Endothelin Receptor Signaling Pathway Involved In Heart Process GBD Domain Binding Storage Vacuole Positive Regulation Of DNA-templated Transcription Initiation CHOP-C/EBP Complex Regulation Of DNA-templated Transcription Initiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Ribonucleoside Binding RNA-directed RNA Polymerase Activity RNA-templated Transcription DNA-directed RNA Polymerase Activity Prostaglandin-I Synthase Activity Glycylpeptide N-tetradecanoyltransferase Activity Protein Lipidation N-terminal Peptidyl-glycine N-myristoylation Peptidyl-lysine N6-myristoyltransferase Activity Positive Regulation Of Ribosome Biogenesis	Intermediate Filament Positive Regulation Of Low-density Lipoprotein Particle Clearance Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Low-density Lipoprotein Particle Clearance
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