NRXN2 and DDX24

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		NRXN2	DDX24
Description		neurexin 2	DEAD-box helicase 24
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Protein-containing Complex Presynaptic Membrane Cell Projection Synapse Glutamatergic Synapse	Nucleus Nucleolus Cytoplasm Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Calcium Channel Regulator Activity Metal Ion Binding Cell Adhesion Molecule Binding Neuroligin Family Protein Binding	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity
	Biological Process	Cell Adhesion Neuron Cell-cell Adhesion Signal Transduction Chemical Synaptic Transmission Neurotransmitter Secretion Synapse Assembly Adult Behavior Social Behavior Vocal Learning Vocalization Behavior Postsynaptic Membrane Assembly Gephyrin Clustering Involved In Postsynaptic Density Assembly Neuroligin Clustering Involved In Postsynaptic Membrane Assembly Postsynaptic Density Protein 95 Clustering Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Postsynapse Assembly	RNA Metabolic Process
Pathways		Neurexins and neuroligins Neurexins and neuroligins Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Bitter alcoholic beverage consumption ( 31046077) Body mass index ( 28892062 29273807) Gout ( 33832965) Lymphocyte count ( 32888494) Post bronchodilator FEV1 in COPD ( 26634245) Serum uric acid levels ( 29403010 30993211) Urate levels ( 21768215 23263486) Urate levels in lean individuals ( 25811787) Urate levels in obese individuals ( 25811787) Urate levels in overweight individuals ( 25811787) Uric acid levels ( 29558500)	Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		9 interacting genes: AFDN CASK DDX24 MACF1 MAPK6 NLGN1 NLGN2 NLGN3 PATJ	37 interacting genes: BCS1L BRCA1 CSNK2A1 EIF3E EP300 FADD FILNC1 GIT1 GLRA2 HSP90AB1 HSPA5 IDO1 ITGB3BP LMNA MDM2 MKS1 MRPL4 NRXN2 PAFAH1B3 PIN1 POLA2 PRF1 PTEN PTPN23 RAE1 RNF10 SPACA9 SPTAN1 TERF1 TERF2 TERF2IP TMEM9B TPI1 TRDMT1 UBE2I USP7 VDAC3
Entrez ID		9379	57062
HPRD ID		11859	05860
Ensembl ID		ENSG00000110076	ENSG00000089737
Uniprot IDs		A0A8I5KY42 P58401 Q9P2S2	Q9GZR7
PDB IDs		4NXR
Enriched GO Terms of Interacting Partners?		Neurexin Family Protein Binding Postsynaptic Membrane Assembly Postsynaptic Membrane Organization Presynaptic Membrane Assembly Neuron To Neuron Synapse Presynaptic Membrane Organization Presynapse Assembly Neuron Cell-cell Adhesion Cell Junction Assembly Cell Adhesion Molecule Binding Presynapse Organization Excitatory Synapse Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of Synaptic Transmission, Glutamatergic Symmetric, GABA-ergic, Inhibitory Synapse Positive Regulation Of Dendritic Spine Development Asymmetric, Glutamatergic, Excitatory Synapse Cell Junction Organization Modulation Of Excitatory Postsynaptic Potential Regulation Of Dendritic Spine Development Terminal Button Organization Membrane Assembly Positive Regulation Of Synapse Assembly Postsynaptic Density Protein 95 Clustering Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Cell Junction Assembly Positive Regulation Of Nervous System Development Synapse Assembly Regulation Of Respiratory Gaseous Exchange By Nervous System Process Neurotransmitter-gated Ion Channel Clustering Positive Regulation Of Cell Junction Assembly Regulation Of Respiratory System Process Regulation Of Nervous System Process Positive Regulation Of Synaptic Transmission, GABAergic Cell Adhesion Positive Regulation Of Synaptic Transmission Regulation Of Nervous System Development Regulation Of Respiratory Gaseous Exchange Regulation Of Synapse Assembly Cell-cell Adhesion Modulation Of Chemical Synaptic Transmission Cell-cell Junction Organization Localization Within Membrane Postsynaptic Specialization Membrane Cell Junction Regulation Of Synaptic Transmission, GABAergic Tight Junction Postsynaptic Membrane Synapse Organization Positive Regulation Of Developmental Process	RNA-templated DNA Biosynthetic Process Shelterin Complex Cellular Component Assembly Nuclear Body Regulation Of Protein Stability Nuclear Telomere Cap Complex G-rich Strand Telomeric DNA Binding Negative Regulation Of Cellular Component Organization Telomere Capping Regulation Of Cellular Component Organization PML Body Regulation Of Telomere Maintenance Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of DNA Recombination At Telomere Organelle Organization Protein Localization To Organelle Negative Regulation Of Macromolecule Metabolic Process Protein Stabilization Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Catabolic Process Telomere Maintenance Via Telomerase P53 Binding Regulation Of Cell Cycle Process Negative Regulation Of Metabolic Process Regulation Of Cell Communication Protein-containing Complex Regulation Of Signaling Regulation Of Organelle Organization Telomeric DNA Binding Negative Regulation Of Protein Metabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Telomere Maintenance Via Telomere Lengthening DNA Biosynthetic Process Nucleoplasm Regulation Of Cell Cycle Telomere Maintenance Receptor Serine/threonine Kinase Binding Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Apoptotic Process Negative Regulation Of Telomere Maintenance Regulation Of DNA Metabolic Process Establishment Of Protein Localization To Organelle Positive Regulation Of Metabolic Process Negative Regulation Of Programmed Cell Death Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Activity Protection From Non-homologous End Joining At Telomere Negative Regulation Of Small Molecule Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?