FBXO44 and BLOC1S1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FBXO44	BLOC1S1
Description		F-box protein 44	biogenesis of lysosomal organelles complex 1 subunit 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Extracellular Space Cytoplasm Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix Lysosome Lysosomal Membrane Early Endosome Cytosol Membrane BLOC-1 Complex Cytoplasmic Side Of Lysosomal Membrane BORC Complex Axon Cytoplasm
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding Transferase Activity Protein-lysine-acetyltransferase Activity
	Biological Process	Glycoprotein Catabolic Process Proteasomal Protein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process ERAD Pathway	Anterograde Axonal Transport Aerobic Respiration Endosomal Transport Peptidyl-lysine Acetylation Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Regulation Of Endosome Size Platelet Dense Granule Organization Regulation Of Lysosome Size Organelle Transport Along Microtubule
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Neurological blood protein biomarker levels ( 31320639)	Refractive error ( 32231278)
Interacting Genes		12 interacting genes: BLOC1S1 BORCS6 BRCA1 HSF2BP ISY1-RAB43 KCNJ5-AS1 MEOX2 PRDM5 SERTAD3 SKP1 SPG21 UBC	18 interacting genes: APP BLOC1S2 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 DCTN2 FBXO44 HGS MAGEB4 MTA1 NOTCH1 PBX2 PELP1 PTN SNAPC5 SNAPIN USHBP1
Entrez ID		93611	2647
HPRD ID		16445	03263
Ensembl ID		ENSG00000132879	ENSG00000135441
Uniprot IDs		B7Z1P2 Q9H4M3	P78537
PDB IDs		3WSO 5B4N
Enriched GO Terms of Interacting Partners?		Regulation Of Lysosome Size BORC Complex Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane Regulation Of Vesicle Size	Anterograde Synaptic Vesicle Transport BLOC-1 Complex Axo-dendritic Transport Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Anterograde Axonal Transport Vesicle Transport Along Microtubule Establishment Of Vesicle Localization Vesicle Cytoskeletal Trafficking Vesicle Localization Axon Cytoplasm Axonal Transport Organelle Transport Along Microtubule Transport Along Microtubule Neuron Projection Development Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Establishment Of Organelle Localization Melanosome Transport Establishment Of Melanosome Localization Pigment Granule Transport Melanosome Localization Pigment Granule Localization Vesicle Organization Plasma Membrane Bounded Cell Projection Organization Microtubule-based Movement Microvesicle Endosome To Melanosome Transport Organelle Localization Cell Projection Organization Microtubule-based Process Cellular Localization Establishment Of Localization In Cell Intracellular Transport Secretion Of Lysosomal Enzymes Pigmentation Positive Regulation Of Pigment Cell Differentiation Regulation Of Lysosome Size BORC Complex Positive Regulation Of Developmental Pigmentation Regulation Of Endosome Size Negative Regulation Of Long-term Synaptic Potentiation Regulation Of Stem Cell Differentiation Cytoplasmic Side Of Lysosomal Membrane Regulation Of Developmental Pigmentation Developmental Pigmentation Chromatin Binding Rhythmic Process Regulation Of Vesicle Size
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