FBXO44 and BORCS6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FBXO44	BORCS6
Description		F-box protein 44	BLOC-1 related complex subunit 6
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Lysosome Lysosomal Membrane Membrane Cytoplasmic Side Of Lysosomal Membrane BORC Complex
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding Identical Protein Binding
	Biological Process	Glycoprotein Catabolic Process Proteasomal Protein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process ERAD Pathway	Lysosome Localization Regulation Of Endosome Size Regulation Of Lysosome Size Organelle Transport Along Microtubule
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		12 interacting genes: BLOC1S1 BORCS6 BRCA1 HSF2BP ISY1-RAB43 KCNJ5-AS1 MEOX2 PRDM5 SERTAD3 SKP1 SPG21 UBC	31 interacting genes: ABI2 AIRIM BEX2 C19orf25 C1orf216 DRC4 EPS8 EXOC8 EXOSC5 FAM161B FAM9C FBXO44 FCHSD2 HAUS1 HGS KANK2 LNX1 MED21 MOS NDEL1 NTAQ1 OSTF1 PKNOX1 PLA2G4A RCOR3 RIBC1 SHPRH SPG21 TACC2 USHBP1 ZNF655
Entrez ID		93611	54785
HPRD ID		16445	13368
Ensembl ID		ENSG00000132879	ENSG00000196544
Uniprot IDs		B7Z1P2 Q9H4M3	Q96GS4
PDB IDs		3WSO 5B4N
Enriched GO Terms of Interacting Partners?		Regulation Of Lysosome Size BORC Complex Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane Regulation Of Vesicle Size
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