FBXO44 and KCNJ5-AS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FBXO44	KCNJ5-AS1
Description		F-box protein 44	KCNJ5 antisense RNA 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Extracellular Region
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Glycoprotein Catabolic Process Proteasomal Protein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process ERAD Pathway
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		12 interacting genes: BLOC1S1 BORCS6 BRCA1 HSF2BP ISY1-RAB43 KCNJ5-AS1 MEOX2 PRDM5 SERTAD3 SKP1 SPG21 UBC	7 interacting genes: APP EFHC1 FBXO44 FRS3 GPSM3 PLEKHF2 TLX3
Entrez ID		93611	219833
HPRD ID		16445	11344
Ensembl ID		ENSG00000132879	ENSG00000174370
Uniprot IDs		B7Z1P2 Q9H4M3
PDB IDs		3WSO 5B4N
Enriched GO Terms of Interacting Partners?		Regulation Of Lysosome Size BORC Complex Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane Regulation Of Vesicle Size	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Central Nervous System Development Intermediate-density Lipoprotein Particle Positive Regulation Of Inflammatory Response Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Positive Regulation Of Chemotaxis Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Positive Regulation Of Leukocyte Chemotaxis Lipoprotein Particle Growth Factor Receptor Binding Main Axon Positive Regulation Of Leukocyte Migration Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Neuron Differentiation Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Early Endosome Membrane Regulation Of Chemotaxis Heparan Sulfate Binding Signaling Receptor Activator Activity
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