MPV17 and SYCE1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
43

Data Source:
BioGRID (two hybrid)

		MPV17	SYCE1
Description		mitochondrial inner membrane protein MPV17	synaptonemal complex central element protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Inner Membrane Peroxisome Peroxisomal Membrane Cytosol Membrane	Synaptonemal Complex Central Element Nucleus Chromosome
	Molecular Function	Channel Activity	Protein Binding
	Biological Process	Glomerular Basement Membrane Development Cellular Response To Reactive Oxygen Species Homeostatic Process Inner Ear Development Transmembrane Transport Regulation Of Mitochondrial DNA Metabolic Process Regulation Of Reactive Oxygen Species Metabolic Process	Synaptonemal Complex Assembly Cell Division Meiotic Cell Cycle Synaptonemal Complex Organization
Pathways		Peroxisomal protein import Peroxisomal protein import	Meiotic synapsis
Drugs
Diseases		Mitochondrial DNA depletion syndrome (MDS)
GWAS
Interacting Genes		2 interacting genes: PEX5 SYCE1	45 interacting genes: ALOX5 ARNT2 BEX2 BFSP2 CBY2 CCDC102B CCHCR1 CFAP100 CINP CNN1 EDRF1 EXOC8 FAM161A FAM161B HAUS1 HMG20B HSPB1 HSPB7 IQUB KAT5 KIFC3 KRT18 MBD3 MPV17 MRFAP1L1 NME7 PSTPIP1 RALBP1 RBCK1 RUNX1T1 SCNM1 SKA1 SMARCE1 SPATC1L SSX2 STX19 TFIP11 TPM3 TRAF1 TRIM41 TSG101 TXN2 VPS25 WASHC3 ZNF124
Entrez ID		4358	93426
HPRD ID		08847	12598
Ensembl ID		ENSG00000115204	ENSG00000171772
Uniprot IDs		A0A0S2Z3Z9 P39210	A0A0B4J1R9 Q8N0S2
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Import Into Peroxisome Matrix, Translocation Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Peroxisome Targeting Sequence Binding Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Membrane Protein Import Into Peroxisome Matrix, Substrate Release Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Carrier Chaperone Central Element Protein Unfolding Peroxisomal Membrane Transport Establishment Of Protein Localization To Peroxisome Protein Import Into Peroxisome Matrix Cerebral Cortex Neuron Differentiation Pexophagy Synaptonemal Complex Synaptonemal Complex Assembly Synaptonemal Complex Organization Receptor Recycling Peroxisome Organization Intracellular Protein Transmembrane Transport Cerebral Cortex Cell Migration Positive Regulation Of Multicellular Organism Growth Very Long-chain Fatty Acid Metabolic Process Forebrain Neuron Differentiation Telencephalon Cell Migration Forebrain Cell Migration Receptor Metabolic Process Peroxisomal Matrix Fatty Acid Beta-oxidation Protein Monoubiquitination Chromosome Organization Involved In Meiotic Cell Cycle Endoplasmic Reticulum Organization Peroxisomal Membrane Regulation Of Multicellular Organism Growth Protein Transmembrane Transport Fatty Acid Oxidation Fatty Acid Catabolic Process Lipid Oxidation Protein Tetramerization Cellular Response To Reactive Oxygen Species Neuromuscular Process Mitochondrial Membrane Organization Meiotic Cell Cycle Peroxisome	Cytoskeleton
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