PRDM6 and ATOSB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRDM6	ATOSB
Description		PR/SET domain 6	atos homolog B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Identical Protein Binding Metal Ion Binding Histone H4K20 Monomethyltransferase Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Regulation Of Gene Expression Neurogenesis Methylation Negative Regulation Of DNA-templated Transcription Negative Regulation Of Smooth Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28892062) Coronary artery disease ( 29212778) Diastolic blood pressure ( 27618447 27841878) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Male-pattern baldness ( 28196072) Mammographic density (dense area) ( 25342443) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Percent mammographic density ( 25342443) Pulse pressure ( 27841878 27618447) QRS duration ( 25035420) Systolic blood pressure ( 27841878 27618447 26390057 30578418)
Interacting Genes		71 interacting genes: ABI2 AGXT AHCYL1 AIRIM ANKS1A AQP1 ARID5A ATOSB ATPAF2 ATXN7L2 BAG3 BANF2 BANP CBFA2T2 CBX8 CCDC120 CCDC57 CCHCR1 CCNL1 CEP57L1 COX5B CSTF2 ELOA ENKD1 EXOSC5 FAM90A1 FHL2 FOXD4L1 FRS3 FTO GADD45GIP1 GEM GPANK1 GRXCR1 HOXC8 IL16 IQUB KANK2 KAT5 KCTD9 KIFC3 LMO1 LMO2 LONRF1 MYOZ3 NCK2 NEK6 NFKBID PATZ1 PIH1D2 PRKAA2 PTK6 QARS1 RAD51D ROPN1 RUNX1T1 SAMD4A SLC19A4P STK16 TCAF1 TEKT4 TLE5 TRIM14 TSGA10 TSGA10IP TSSK3 TTC23 TYW2 UBASH3A USP54 ZFYVE26	64 interacting genes: ABI2 AKAP8L APP BAG4 C11orf65 C7orf57 CALCOCO2 CCDC125 CCDC33 CCDC85B CEP70 CFTR CYSRT1 DIP2A DNAJA3 EFHC2 EYA2 FHL2 FHL5 GOLGA2 GPRASP3 HSF2BP HSPB8 IKZF1 KIF20A KPNA3 KPNA5 KRT34 KRTAP19-5 KRTAP19-6 KRTAP6-2 KRTAP6-3 LMO2 LZTS2 MDFI MID2 MKRN3 MYO1F MYO5B MYOZ3 NCOA5 PDLIM7 PFDN5 PICK1 PRDM6 PTPN21 RBM11 SFMBT1 SLAIN1 SORBS3 TBC1D23 TEPSIN TLE5 TRAF2 TRAF4 TRIM27 VPS9D1 WWOX WWP2 ZMYND12 ZNF219 ZNF572 ZNF655 ZRANB1
Entrez ID		93166	80256
HPRD ID		19698	13869
Ensembl ID		ENSG00000061455	ENSG00000005238
Uniprot IDs		Q9NQX0	Q7L5A3
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding	Identical Protein Binding Negative Regulation Of RNA Metabolic Process Protein Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Cytoplasm Cytoskeleton Regulation Of Supramolecular Fiber Organization Cytosol Regulation Of Wnt Signaling Pathway Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Protein Targeting To Mitochondrion Regulation Of Actin Nucleation Intermediate Filament Regulation Of RNA Metabolic Process Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Neuron Projection Organization Zinc Ion Binding NLS-dependent Protein Nuclear Import Complex Positive Regulation Of Cytoskeleton Organization Thioesterase Binding
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