PRDM6 and BANP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRDM6	BANP
Description		PR/SET domain 6	BTG3 associated nuclear protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Nuclear Body Nuclear Speck
	Molecular Function	Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Identical Protein Binding Metal Ion Binding Histone H4K20 Monomethyltransferase Activity	DNA Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Regulation Of Gene Expression Neurogenesis Methylation Negative Regulation Of DNA-templated Transcription Negative Regulation Of Smooth Muscle Cell Differentiation	Chromatin Organization
Pathways			Regulation of TP53 Activity through Association with Co-factors Degradation of CDH1
Drugs
Diseases
GWAS		Body mass index ( 28892062) Coronary artery disease ( 29212778) Diastolic blood pressure ( 27618447 27841878) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Male-pattern baldness ( 28196072) Mammographic density (dense area) ( 25342443) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Percent mammographic density ( 25342443) Pulse pressure ( 27841878 27618447) QRS duration ( 25035420) Systolic blood pressure ( 27841878 27618447 26390057 30578418)	Apolipoprotein A1 levels ( 32203549) Central corneal thickness ( 20719862 28171582) Corneal structure ( 23291589) HDL cholesterol levels ( 32203549) Intraocular pressure ( 29235454) Keratoconus ( 33649486) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549)
Interacting Genes		71 interacting genes: ABI2 AGXT AHCYL1 AIRIM ANKS1A AQP1 ARID5A ATOSB ATPAF2 ATXN7L2 BAG3 BANF2 BANP CBFA2T2 CBX8 CCDC120 CCDC57 CCHCR1 CCNL1 CEP57L1 COX5B CSTF2 ELOA ENKD1 EXOSC5 FAM90A1 FHL2 FOXD4L1 FRS3 FTO GADD45GIP1 GEM GPANK1 GRXCR1 HOXC8 IL16 IQUB KANK2 KAT5 KCTD9 KIFC3 LMO1 LMO2 LONRF1 MYOZ3 NCK2 NEK6 NFKBID PATZ1 PIH1D2 PRKAA2 PTK6 QARS1 RAD51D ROPN1 RUNX1T1 SAMD4A SLC19A4P STK16 TCAF1 TEKT4 TLE5 TRIM14 TSGA10 TSGA10IP TSSK3 TTC23 TYW2 UBASH3A USP54 ZFYVE26	193 interacting genes: ABLIM3 ADAM15 AFG1L ALAS2 ANAPC11 ANKRD55 ANTKMT ARID5A ATF2 ATXN7L2 BAG5 BICRAL BLZF1 BOC BTG3 C1orf94 C1QTNF2 C22orf15 C22orf39 C3orf36 CAMK2D CBX8 CCDC26 CCDC74B CDC7 CDSN CDX4 CEP76 CFAP206 CHRDL2 COL10A1 CRX CSNK2B CTSZ CYTOR DCDC2B DLX3 DNAJA4 ENKD1 EPHA10 ESM1 FAM117B FAM120C FAM217B FAM222B FAM90A1 FARS2 FHL2 FHL5 FLOT1 FOXM1 FOXR1 GARIN6 GAS2L2 GFM2 GOLGA6L9 HAPLN2 HEYL HHIPL1 HIVEP1 HMGB3P1 HNRNPLL HSFY1 IDO2 IGF1 IGFN1 INO80B ISCU KCTD9 KHDC4 KLF15 KRTAP8-1 L3MBTL3 LAP3 LENG1 LGALS14 LGALS4 LHX4 LHX8 LIN54 LINC01547 LMO1 LMO2 LMO3 LMO4 LRIF1 LSM2 MAP2K1 MAPK1 MAX MDFI MEOX1 MEOX2 MIR4435-2HG MRPL28 MRRF MSRB3 MTERF4 MVP NEDD9 NFYA NMNAT1 NOTO NRIP2 PANX2 PARD6B PAX6 PHF21A PHF21B PID1 PIH1D2 PIK3C2G PIM1 PML PNRC2 POGZ POLDIP3 POLR2L POU6F2 PPIB PPIC PPIF PRDM6 PRKAB2 PRKCH PRPF39 PRR20A PRR20B PRR20C PRR20D PRR20E PRR23B PRR34 PSMD9 PSORS1C2 RAB3IP RAD54L2 RBM39 RBPMS REL RELA RHNO1 RHOH RHOQ RIDA RIMS3 RPP25 RYBP SAPCD1 SCN5A SH3RF2 SLC16A3 SLC19A4P SNAPIN SNRPB SNX5 SP2 SP4 SPACA6 SPANXN2 SPMIP2 SRARP STK38 STOX1 TAF6 TERF2 TERF2IP TNXB TOX TOX4 TP53 TRAF2 TRAF4 TRIM35 TROAP TTC23 UBAP2 UBE2I VEZF1 XAGE1B YJU2 ZBTB4 ZC2HC1C ZMIZ2 ZMYM6 ZNF410 ZNF438 ZNF471 ZNF474 ZNF488 ZNF512B ZNF580 ZNF581
Entrez ID		93166	54971
HPRD ID		19698	16538
Ensembl ID		ENSG00000061455	ENSG00000172530
Uniprot IDs		Q9NQX0	A0A0S2Z5C2 A0A0S2Z5M2 A0A804HKG3 B3KM38 B4DE54 Q8N9N5
PDB IDs			7YUG 7YUK 8HTX 8YZT
Enriched GO Terms of Interacting Partners?		Protein Binding	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Protein Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Chromatin Positive Regulation Of Macromolecule Metabolic Process Nucleus DNA Binding Positive Regulation Of Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Nucleoplasm RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Binding Negative Regulation Of Macromolecule Metabolic Process Zinc Ion Binding Sequence-specific Double-stranded DNA Binding Cyclosporin A Binding Negative Regulation Of DNA Recombination At Telomere Positive Regulation Of Kinase Activity Negative Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of RNA Metabolic Process Protein Kinase Binding Regulation Of Kinase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Cyclin-dependent Protein Kinase Activity
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