CD19 and CD79B

Number of citations of the paper that reports this interaction (PMID 9120258)
10

Data Source:
HPRD (in vivo)

		CD19	CD79B
Gene Name		CD19 molecule	CD79b molecule, immunoglobulin-associated beta
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Protein Complex Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane B Cell Receptor Complex Extracellular Vesicular Exosome
	Molecular Function	Receptor Signaling Protein Activity	Transmembrane Signaling Receptor Activity
	Biological Process	Cellular Defense Response Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Fc-epsilon Receptor Signaling Pathway Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Regulation Of Immune Response B Cell Receptor Signaling Pathway Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol	Immune Response Signal Transduction B Cell Receptor Signaling Pathway
Pathways		Signaling by the B Cell Receptor (BCR) Signaling by FGFR in disease PIP3 activates AKT signaling Signaling by EGFRvIII in Cancer Signaling by SCF-KIT Downstream signaling events of B Cell Receptor (BCR) DAP12 signaling PI3K/AKT activation PI-3K cascade PI3K events in ERBB2 signaling Downstream signaling of activated FGFR Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Innate Immune System Signaling by PDGF Signalling by NGF DAP12 interactions GAB1 signalosome Signaling by Ligand-Responsive EGFR Variants in Cancer NGF signalling via TRKA from the plasma membrane Signaling by ERBB4 Signaling by Overexpressed Wild-Type EGFR in Cancer Role of LAT2/NTAL/LAB on calcium mobilization Constitutive PI3K/AKT Signaling in Cancer PI3K events in ERBB4 signaling Signaling by FGFR Signaling by ERBB2 Signaling by EGFR Downstream signal transduction Fc epsilon receptor (FCERI) signaling Signaling by EGFR in Cancer PI3K/AKT Signaling in Cancer Adaptive Immune System	Signaling by the B Cell Receptor (BCR) Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Adaptive Immune System
Drugs
Diseases
GWAS		Crohn's disease ( 21102463)
Protein-Protein Interactions		21 interactors: ABL1 BTK CBL CD22 CD79A CD79B CD81 CD82 CD9 CR2 ECT2 FYN GRB2 LYN MAPK1 PIK3R1 PLCG2 SOS1 SYK VAV1 VAV2	13 interactors: BLK CD19 CD3E CD5 CD79A FYN LCK LYN PTK2 PTPN6 SGTA SYK ZAP70
Entrez ID		930	974
HPRD ID		00113	00922
Ensembl ID		ENSG00000177455	ENSG00000007312
Uniprot IDs		P15391	P40259
PDB IDs			3KG5
Enriched GO Terms of Interacting Partners?		Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Immune Response Cell Activation Fc Receptor Signaling Pathway Platelet Activation B Cell Receptor Signaling Pathway Positive Regulation Of Immune Response Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune System Process Fc-epsilon Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Regulation Of Immune System Process Blood Coagulation Hemostasis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Phagocytosis Regulation Of Body Fluid Levels Innate Immune Response Wound Healing Enzyme Linked Receptor Protein Signaling Pathway Response To Wounding Immune Response Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Surface Receptor Signaling Pathway Leukocyte Activation Immune System Process Defense Response Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Lymphocyte Activation Endocytosis Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Activation Cellular Response To Fibroblast Growth Factor Stimulus Peptidyl-tyrosine Autophosphorylation Response To Fibroblast Growth Factor Intracellular Signal Transduction Vesicle-mediated Transport Cellular Response To Growth Factor Stimulus Leukocyte Migration Response To Growth Factor Response To Organic Substance Regulation Of Lymphocyte Activation Chemotaxis Locomotion	Antigen Receptor-mediated Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway B Cell Receptor Signaling Pathway Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Immune System Process Positive Regulation Of Immune Response Regulation Of Immune System Process Regulation Of Immune Response Regulation Of Cell-cell Adhesion Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Positive Regulation Of Cell-cell Adhesion Peptidyl-tyrosine Phosphorylation Regulation Of T Cell Activation Positive Regulation Of Cell Activation T Cell Costimulation Enzyme Linked Receptor Protein Signaling Pathway Protein Autophosphorylation Regulation Of Cell Adhesion Positive Regulation Of Cell Adhesion Immune System Process Regulation Of Lymphocyte Activation Regulation Of Cell Activation Leukocyte Activation Innate Immune Response Homotypic Cell-cell Adhesion Leukocyte Differentiation Hemopoiesis Platelet Activation Lymphocyte Activation Immune System Development Leukocyte Migration Lymphocyte Differentiation Positive Regulation Of Intracellular Signal Transduction Immune Response Fc Receptor Signaling Pathway Defense Response Single Organismal Cell-cell Adhesion T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Regulation Of Cell Adhesion Mediated By Integrin Peptidyl-amino Acid Modification Cellular Response To Peptide Hormone Stimulus Leukocyte Cell-cell Adhesion
Tagcloud ?		bmt cd11b cd11c cd45 cd5 cytometric cytopenias deferral definitive dilemma gating hairy hcl hodgkin immunophenotyping maturing mdf morphologic multidimensional myeloblast myelodysplasia pancytopenia phenotyping presumptive refined reside scatter scheme unexplained	abc capillary card11 constitutes deregulation diffuse dlbcl employing ezh2 gcb germinal gold hallmarks harbor harboring hotspot hotspots immunochemotherapy l265p mediastinal myd88 pmbl pmbls pose pyrosequencing thoroughly unlike utilizing vital
Tagcloud (Difference) ?		bmt cd11b cd11c cd45 cd5 cytometric cytopenias deferral definitive dilemma gating hairy hcl hodgkin immunophenotyping maturing mdf morphologic multidimensional myeloblast myelodysplasia pancytopenia phenotyping presumptive refined reside scatter scheme unexplained	abc capillary card11 constitutes deregulation diffuse dlbcl employing ezh2 gcb germinal gold hallmarks harbor harboring hotspot hotspots immunochemotherapy l265p mediastinal myd88 pmbl pmbls pose pyrosequencing thoroughly unlike utilizing vital
Tagcloud (Intersection) ?