CD19 and CD79A

Number of citations of the paper that reports this interaction (PMID 9120258)
10

Data Source:
HPRD (in vivo)

		CD19	CD79A
Gene Name		CD19 molecule	CD79a molecule, immunoglobulin-associated alpha
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Protein Complex Extracellular Vesicular Exosome	Multivesicular Body Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane B Cell Receptor Complex Membrane Raft
	Molecular Function	Receptor Signaling Protein Activity	Transmembrane Signaling Receptor Activity
	Biological Process	Cellular Defense Response Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Fc-epsilon Receptor Signaling Pathway Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Regulation Of Immune Response B Cell Receptor Signaling Pathway Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol	B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway
Pathways		Signaling by the B Cell Receptor (BCR) Signaling by FGFR in disease PIP3 activates AKT signaling Signaling by EGFRvIII in Cancer Signaling by SCF-KIT Downstream signaling events of B Cell Receptor (BCR) DAP12 signaling PI3K/AKT activation PI-3K cascade PI3K events in ERBB2 signaling Downstream signaling of activated FGFR Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Innate Immune System Signaling by PDGF Signalling by NGF DAP12 interactions GAB1 signalosome Signaling by Ligand-Responsive EGFR Variants in Cancer NGF signalling via TRKA from the plasma membrane Signaling by ERBB4 Signaling by Overexpressed Wild-Type EGFR in Cancer Role of LAT2/NTAL/LAB on calcium mobilization Constitutive PI3K/AKT Signaling in Cancer PI3K events in ERBB4 signaling Signaling by FGFR Signaling by ERBB2 Signaling by EGFR Downstream signal transduction Fc epsilon receptor (FCERI) signaling Signaling by EGFR in Cancer PI3K/AKT Signaling in Cancer Adaptive Immune System	Signaling by the B Cell Receptor (BCR) Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Adaptive Immune System
Drugs
Diseases
GWAS		Crohn's disease ( 21102463)
Protein-Protein Interactions		21 interactors: ABL1 BTK CBL CD22 CD79A CD79B CD81 CD82 CD9 CR2 ECT2 FYN GRB2 LYN MAPK1 PIK3R1 PLCG2 SOS1 SYK VAV1 VAV2	17 interactors: BLK BLNK CD19 CD5 CD79B FANCA FATE1 FCAR FYN HCLS1 IGHM IGJ LCK LYN PIGR PTPN6 SYK
Entrez ID		930	973
HPRD ID		00113	00203
Ensembl ID		ENSG00000177455	ENSG00000105369
Uniprot IDs		P15391	P11912
PDB IDs			1CV9
Enriched GO Terms of Interacting Partners?		Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Immune Response Cell Activation Fc Receptor Signaling Pathway Platelet Activation B Cell Receptor Signaling Pathway Positive Regulation Of Immune Response Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune System Process Fc-epsilon Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Regulation Of Immune System Process Blood Coagulation Hemostasis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Phagocytosis Regulation Of Body Fluid Levels Innate Immune Response Wound Healing Enzyme Linked Receptor Protein Signaling Pathway Response To Wounding Immune Response Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Surface Receptor Signaling Pathway Leukocyte Activation Immune System Process Defense Response Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Lymphocyte Activation Endocytosis Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Activation Cellular Response To Fibroblast Growth Factor Stimulus Peptidyl-tyrosine Autophosphorylation Response To Fibroblast Growth Factor Intracellular Signal Transduction Vesicle-mediated Transport Cellular Response To Growth Factor Stimulus Leukocyte Migration Response To Growth Factor Response To Organic Substance Regulation Of Lymphocyte Activation Chemotaxis Locomotion	B Cell Receptor Signaling Pathway Immune System Process Antigen Receptor-mediated Signaling Pathway Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Immune System Process Regulation Of Immune System Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Regulation Of Immune Response T Cell Costimulation Enzyme Linked Receptor Protein Signaling Pathway Defense Response Positive Regulation Of Immune Response Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Fc Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Regulation Of T Cell Activation Positive Regulation Of Cell Activation Response To Stimulus Hemopoiesis Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Cell Activation Regulation Of Lymphocyte Activation Platelet Activation Immune System Development Protein Autophosphorylation Regulation Of Peptidyl-tyrosine Phosphorylation Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Regulation Of Cell Activation Leukocyte Activation Intracellular Signal Transduction Cellular Response To Peptide Hormone Stimulus Response To Stress Cellular Response To Peptide Homotypic Cell-cell Adhesion Regulation Of Cell Proliferation Regulation Of Cell Adhesion Leukocyte Differentiation Regulation Of Cellular Localization Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Tagcloud ?		bmt cd11b cd11c cd45 cd5 cytometric cytopenias deferral definitive dilemma gating hairy hcl hodgkin immunophenotyping maturing mdf morphologic multidimensional myeloblast myelodysplasia pancytopenia phenotyping presumptive refined reside scatter scheme unexplained	abdomen axillae bence cd138 cd20 cd56 dermis disappearing emp enlarged extramedullar fig immunohistological inguinal jones microglobulin monotypic painless pcp pcps plasmacytoid plasmacytoma pointed reappeared runs subcutis temporarily vincristine
Tagcloud (Difference) ?		bmt cd11b cd11c cd45 cd5 cytometric cytopenias deferral definitive dilemma gating hairy hcl hodgkin immunophenotyping maturing mdf morphologic multidimensional myeloblast myelodysplasia pancytopenia phenotyping presumptive refined reside scatter scheme unexplained	abdomen axillae bence cd138 cd20 cd56 dermis disappearing emp enlarged extramedullar fig immunohistological inguinal jones microglobulin monotypic painless pcp pcps plasmacytoid plasmacytoma pointed reappeared runs subcutis temporarily vincristine
Tagcloud (Intersection) ?