AIMP1 and RARS

Number of citations of the paper that reports this interaction (PMID 10358004)
14

Data Source:
HPRD (in vitro)

		AIMP1	RARS
Gene Name		aminoacyl tRNA synthetase complex-interacting multifunctional protein 1	arginyl-tRNA synthetase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Cell Surface Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex Transport Vesicle	Nucleoplasm Cytoplasm Mitochondrion Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex Extracellular Vesicular Exosome
	Molecular Function	TRNA Binding Methionine-tRNA Ligase Activity Cytokine Activity Protein Binding Protein Homodimerization Activity	TRNA Binding Arginine-tRNA Ligase Activity Protein Binding ATP Binding Arginine Binding
	Biological Process	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Glucose Metabolic Process TRNA Aminoacylation For Protein Translation Methionyl-tRNA Aminoacylation Apoptotic Process Chemotaxis Inflammatory Response Cell Adhesion Signal Transduction Cell-cell Signaling Response To Wounding Gene Expression Leukocyte Migration	TRNA Aminoacylation For Protein Translation Arginyl-tRNA Aminoacylation Gene Expression
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation	Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AIMP2 APP ATP5A1 IQGAP1 MAPK14 MAPK8 RARS TSNAX	3 interactors: AIMP1 EPRS QARS
Entrez ID		9255	5917
HPRD ID		04676	00142
Ensembl ID		ENSG00000164022	ENSG00000113643
Uniprot IDs		B4DNK3 Q12904	F5H3T8 P54136
PDB IDs		1E7Z 1EUJ 1FL0
Enriched GO Terms of Interacting Partners?		Small Molecule Metabolic Process Developmental Growth Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Apoptotic Process Toll-like Receptor 2 Signaling Pathway Regulation Of Cellular Protein Metabolic Process Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Programmed Cell Death MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Cell Death Death MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Toll-like Receptor 4 Signaling Pathway P38MAPK Cascade Response To Radiation Developmental Cell Growth Positive Regulation Of Protein Metabolic Process Growth TRNA Aminoacylation For Protein Translation Toll-like Receptor Signaling Pathway TRNA Aminoacylation Stress-activated MAPK Cascade Synaptic Growth At Neuromuscular Junction Peptidyl-serine Phosphorylation Stress-activated Protein Kinase Signaling Cascade Cellular Response To Growth Factor Stimulus Response To Growth Factor Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cellular Response To Inorganic Substance Positive Regulation Of Catalytic Activity Collateral Sprouting In Absence Of Injury Nucleobase-containing Compound Metabolic Process Activation Of Innate Immune Response Developmental Growth Involved In Morphogenesis Regulation Of Protein Binding Cell Growth Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Establishment Of Protein Localization Cellular Response To Lipopolysaccharide Cellular Metabolic Process Multicellular Organismal Development Cellular Response To Molecule Of Bacterial Origin	Prolyl-tRNA Aminoacylation Glutamyl-tRNA Aminoacylation TRNA Aminoacylation For Protein Translation TRNA Aminoacylation TRNA Metabolic Process Cellular Amino Acid Metabolic Process NcRNA Metabolic Process Translation Negative Regulation Of Translation Carboxylic Acid Metabolic Process Cellular Response To Interferon-gamma Organic Acid Metabolic Process Glutaminyl-tRNA Aminoacylation Response To Interferon-gamma Defense Response Regulation Of Translation Immune System Process Small Molecule Metabolic Process Posttranscriptional Regulation Of Gene Expression Cellular Response To Cytokine Stimulus RNA Metabolic Process Response To Cytokine Response To Stress Gene Expression Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Endothelial Cell Proliferation Negative Regulation Of Protein Metabolic Process Protein Complex Assembly Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Immune Response Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Endothelial Cell Proliferation Nitrogen Compound Metabolic Process Protein Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Cellular Response To Organic Substance Glucose Metabolic Process Cellular Component Assembly Regulation Of Cellular Protein Metabolic Process Cellular Response To Stimulus Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		basalis cycle cytokine diestrus dynamic element endometrium epithelium ere estrogen estrous estrus functionalis give glandular layers localized luminal might multifunctional ovarectomized regulator remodel remodeling stromal transcripts us uterine uterus	ap argue capable dimeric dimerization disrupt fos glucocorticoid heterodimerization homo homodimerization hraralpha hybrid indirect interfere jun liganded occurring promoters protooncoproteins raralpha repress repression responsive retinoic retinoid rxr rxrs
Tagcloud (Difference) ?		basalis cycle cytokine diestrus dynamic element endometrium epithelium ere estrogen estrous estrus functionalis give glandular layers localized luminal might multifunctional ovarectomized regulator remodel remodeling stromal transcripts us uterine uterus	ap argue capable dimeric dimerization disrupt fos glucocorticoid heterodimerization homo homodimerization hraralpha hybrid indirect interfere jun liganded occurring promoters protooncoproteins raralpha repress repression responsive retinoic retinoid rxr rxrs
Tagcloud (Intersection) ?