RARS1 and AIMP1

Number of citations of the paper that reports this interaction (PubMedID 10358004)
0

Data Source:
HPRD (in vitro)

		RARS1	AIMP1
Description		arginyl-tRNA synthetase 1	aminoacyl tRNA synthetase complex interacting multifunctional protein 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex Extracellular Exosome	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Cell Surface Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex
	Molecular Function	TRNA Binding Nucleotide Binding Aminoacyl-tRNA Ligase Activity Arginine-tRNA Ligase Activity Protein Binding ATP Binding Ligase Activity Arginine Binding Cadherin Binding	TRNA Binding RNA Binding Cytokine Activity Protein Binding Protein Homodimerization Activity GTPase Binding
	Biological Process	Translation TRNA Aminoacylation For Protein Translation Arginyl-tRNA Aminoacylation	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Translation Apoptotic Process Inflammatory Response Signal Transduction Cell-cell Signaling Blood Vessel Morphogenesis Leukocyte Migration Defense Response To Virus Positive Regulation Of Glucagon Secretion
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation Transcriptional and post-translational regulation of MITF-M expression and activity	Selenoamino acid metabolism Cytosolic tRNA aminoacylation Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs
Diseases			Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS
Interacting Genes		79 interacting genes: AIMP1 CDC42 CEBPA EPRS1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR25 MIR29A MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OGT QARS1 SUMO2 WBP4 ZNF521	51 interacting genes: AIMP2 APP ATP5F1A HOMER1 IQGAP1 LINC01232 MAPK14 MAPK8 MIR106B MIR107 MIR122 MIR128-1 MIR128-2 MIR138-2 MIR140 MIR15A MIR15B MIR17 MIR199A1 MIR199A2 MIR19B1 MIR19B2 MIR205 MIR206 MIR20B MIR214 MIR222 MIR25 MIR29C MIR31 MIR34A MIR34B MIR34C MIR451A MIR7-1 MIR7-2 MIR7-3 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7I OPTN RARS1 SUMO2 TSNAX
Entrez ID		5917	9255
HPRD ID		00142	04676
Ensembl ID		ENSG00000113643	ENSG00000164022
Uniprot IDs		P54136	B4DNK3 Q12904
PDB IDs		4Q2T 4Q2X 4Q2Y 4R3Z 4ZAJ	1E7Z 1EUJ 1FL0 4R3Z 8J9S 8ONG
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization RNA Destabilization Negative Regulation Of Cell Migration Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Motility Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Locomotion Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Angiogenesis Regulation Of Metabolic Process Regulation Of Translation Regulation Of Vasculature Development Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cytokine Production Negative Regulation Of Multicellular Organismal Process Regulation Of MRNA Stability Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Protein Metabolic Process Negative Regulation Of Developmental Process Regulation Of RNA Stability Regulation Of Endothelial Cell Migration Extracellular Space Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Motility Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway	Regulatory NcRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Extracellular Vesicle Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Vascular Endothelial Growth Factor Production MRNA Destabilization Regulation Of Gene Expression RNA Destabilization Negative Regulation Of Cytokine Production Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of MRNA Catabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Metabolic Process Positive Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Positive Regulation Of Connective Tissue Replacement Regulation Of Angiogenesis Regulation Of RNA Stability Regulation Of Vasculature Development Regulation Of Cytokine Production Negative Regulation Of Angiogenesis Regulation Of Connective Tissue Replacement Negative Regulation Of Vasculature Development Negative Regulation Of Translation Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Endothelial Cell Migration Negative Regulation Of Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Cell Motility Regulation Of Cell Migration Involved In Sprouting Angiogenesis Extracellular Space Negative Regulation Of Locomotion Positive Regulation Of Tissue Remodeling Regulation Of MRNA Metabolic Process Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?