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IL32 and PRTN3
Number of citations of the paper that reports this interaction (PubMedID
16488976
)
49
Data Source:
HPRD
(in vitro)
IL32
PRTN3
Description
interleukin 32
proteinase 3
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytosol
Membrane
Extracellular Region
Extracellular Space
Cytosol
Plasma Membrane
Membrane
Extracellular Matrix
Azurophil Granule Lumen
Plasma Membrane Raft
Membrane Raft
Extracellular Exosome
Molecular Function
Cytokine Activity
Protein Binding
Serine-type Endopeptidase Activity
Signaling Receptor Binding
Protein Binding
Peptidase Activity
Serine-type Peptidase Activity
Hydrolase Activity
Enzyme Binding
Biological Process
Defense Response
Immune Response
Cell Adhesion
Signal Transduction
Positive Regulation Of Gene Expression
Positive Regulation Of Type III Interferon Production
Negative Regulation Of Viral Life Cycle
Proteolysis
Membrane Protein Ectodomain Proteolysis
Positive Regulation Of Cell Population Proliferation
Antimicrobial Humoral Response
Collagen Catabolic Process
Positive Regulation Of GTPase Activity
Cell-cell Junction Maintenance
Negative Regulation Of Phagocytosis
Neutrophil Extravasation
Mature Conventional Dendritic Cell Differentiation
Pathways
Other interleukin signaling
RAC3 GTPase cycle
Common Pathway of Fibrin Clot Formation
Other interleukin signaling
Neutrophil degranulation
Antimicrobial peptides
Drugs
Elafin
Diseases
GWAS
Alanine aminotransferase levels (
34315874
)
Aspartate aminotransferase levels (
34315874
)
HIV-1 susceptibility (
22174851
)
Liver enzyme levels (alanine transaminase) (
33972514
)
Antineutrophil cytoplasmic antibody-associated vasculitis (
28029757
)
Basophil count (
32888494
)
Basophil percentage of granulocytes (
27863252
)
Basophil percentage of white cells (
27863252
32888494
)
Blood protein levels (
30072576
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Monocyte count (
32888494
)
Monocyte percentage of white cells (
27863252
32888494
)
White blood cell count (basophil) (
27863252
)
Interacting Genes
11 interacting genes:
C1QB
HSPA8
KPNA5
NDN
NQO2
PRTN3
RHBDD2
RPL4
SNRNP70
TUT1
ZFPM2
13 interacting genes:
CAMP
ELN
F2R
F2RL1
IL1B
IL32
ITGB2
RELA
SERPINA1
SERPINB1
SERPINB13
SMAD3
TNF
Entrez ID
9235
5657
HPRD ID
09346
01512
Ensembl ID
ENSG00000008517
ENSG00000196415
Uniprot IDs
C6GKH1
G3LU47
P24001
P24158
PDB IDs
1FUJ
Enriched GO Terms of Interacting Partners
?
Regulation Of Interleukin-1 Beta Production
Regulation Of Interleukin-1 Production
Positive Regulation Of Interleukin-8 Production
Regulation Of Interleukin-8 Production
Positive Regulation Of Cytokine Production
Regulation Of Cytokine Production
Positive Regulation Of Interleukin-1 Beta Production
Inflammatory Response
Positive Regulation Of Interleukin-1 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Nitric Oxide Metabolic Process
Regulation Of Establishment Of Protein Localization
Defense Response
Positive Regulation Of Establishment Of Protein Localization
Regulation Of Interleukin-6 Production
Regulation Of Nitric Oxide Biosynthetic Process
Regulation Of Nitric Oxide Metabolic Process
Cell Activation
Positive Regulation Of Chemokine Production
Positive Regulation Of Multicellular Organismal Process
Regulation Of Protein Transport
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of Humoral Immune Response
Positive Regulation Of Gene Expression
Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Regulation Of Chemokine Production
Positive Regulation Of Protein Transport
Positive Regulation Of Transport
Regulation Of Protein Secretion
Immune System Process
Negative Regulation Of Apoptotic Process
Protease Binding
Negative Regulation Of MiRNA Transcription
Negative Regulation Of Programmed Cell Death
Regulation Of Protein Localization
Regulation Of Renin Secretion Into Blood Stream
Regulation Of Secretion By Cell
Regulation Of Immune Response
Response To Lipopolysaccharide
Myeloid Leukocyte Activation
Regulation Of Programmed Cell Death
Regulation Of Canonical NF-kappaB Signal Transduction
Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Regulation Of Angiogenesis
Regulation Of Wound Healing
Regulation Of Vasculature Development
Response To Molecule Of Bacterial Origin
Regulation Of Secretion
Regulation Of Protein Metabolic Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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