LRAT and RBP1

Number of citations of the paper that reports this interaction (PMID 1322170)
25

Data Source:
HPRD (in vitro)

		LRAT	RBP1
Gene Name		lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)	retinol binding protein 1, cellular
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Multivesicular Body Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Cytosol
	Molecular Function	Retinoic Acid Binding Transferase Activity, Transferring Acyl Groups Retinol Binding Phosphatidylcholine-retinol O-acyltransferase Activity	Transporter Activity Retinoid Binding Retinal Binding Retinol Binding
	Biological Process	Retinoid Metabolic Process Vitamin A Metabolic Process Visual Perception Phototransduction, Visible Light Positive Regulation Of Lipid Transport Retinol Metabolic Process Retinoic Acid Metabolic Process	Retinoid Metabolic Process Vitamin A Metabolic Process Transport Phototransduction, Visible Light
Pathways		Visual phototransduction The canonical retinoid cycle in rods (twilight vision) Retinoid cycle disease events Diseases associated with visual transduction Retinoid metabolism and transport	Visual phototransduction The canonical retinoid cycle in rods (twilight vision) Retinoid cycle disease events Diseases associated with visual transduction Retinoid metabolism and transport
Drugs		Vitamin A	Vitamin A Acitretin
Diseases
GWAS
Protein-Protein Interactions		2 interactors: RBP1 RBP2	14 interactors: BRMS1 BRMS1L HDAC1 HDAC2 IKBKG ING1 LINC00152 LRAT LRP2 MED26 RBBP4 RBBP7 SAP30 SIN3A
Entrez ID		9227	5947
HPRD ID		05332	07036
Ensembl ID		ENSG00000121207	ENSG00000114115
Uniprot IDs		O95237	P09455
PDB IDs
Enriched GO Terms of Interacting Partners?		Vitamin A Metabolic Process Phototransduction, Visible Light Retinoid Metabolic Process Diterpenoid Metabolic Process Detection Of Visible Light Phototransduction Detection Of Light Stimulus Vitamin Metabolic Process Isoprenoid Metabolic Process Detection Of Abiotic Stimulus Negative Regulation Of Histone Deacetylase Activity Response To Light Stimulus Response To Radiation Negative Regulation Of Histone Deacetylation Regulation Of Histone Deacetylase Activity Establishment Of Sertoli Cell Barrier Detection Of Stimulus Chromatin Modification Histone H4-K20 Trimethylation Histone H3-K9 Trimethylation Chromatin Organization Histone H3-K4 Trimethylation Transcription From RNA Polymerase II Promoter Histone H4-K20 Methylation Cellular Lipid Metabolic Process Sertoli Cell Development Histone H3-K9 Methylation Chromosome Organization Glutamate Secretion Epithelium Development Response To Abiotic Stimulus Peptidyl-lysine Trimethylation Regulation Of Gene Expression By Genetic Imprinting Sertoli Cell Differentiation Histone H3-K4 Methylation Genetic Imprinting Lipid Metabolic Process Histone H3-K9 Modification Regulation Of Histone Deacetylation Positive Regulation Of Transcription, DNA-templated Erythrocyte Development Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Protein Deacetylation Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Phosphatase Activity Acid Secretion Tissue Development Negative Regulation Of Dephosphorylation Response To External Stimulus	Negative Regulation Of Gene Expression, Epigenetic Chromatin Organization Histone Deacetylation Protein Deacetylation Chromatin Modification Chromosome Organization Regulation Of Gene Expression, Epigenetic Transcription, DNA-templated RNA Biosynthetic Process ATP-dependent Chromatin Remodeling Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of Transcription, DNA-templated RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Expression Histone Modification Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Chromatin Remodeling Organelle Organization Fungiform Papilla Formation Fungiform Papilla Morphogenesis Nucleobase-containing Compound Metabolic Process Positive Regulation Of Receptor Biosynthetic Process Fungiform Papilla Development Heterocycle Metabolic Process Eyelid Development In Camera-type Eye Cellular Aromatic Compound Metabolic Process Hair Follicle Placode Formation Cellular Nitrogen Compound Metabolic Process Tongue Morphogenesis Regulation Of Receptor Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Histone H4 Deacetylation Nitrogen Compound Metabolic Process Regulation Of Cell Death CENP-A Containing Nucleosome Assembly Histone H3 Deacetylation Regulation Of Metabolic Process
Tagcloud ?		am580 analog cis equal ester esterifies extremely hepatic homogenates implicate microsomal molar natural negligible pan pmol predominant r2 rars re retinoid retinoids retinol retinyl retro storage trans uab8	ascl2 c4b dab2ip dlk1 eya4 fabp3 fzd9 gas7 hdac9 hoxa11 hoxa5 hoxa9 hoxb13 ihh ipf1 isl1 mest mme pax6 ptgs2 rassf1 scgb3a1 sept5 serpina5 sox1 sox17 tbx1 tff1 thy1
Tagcloud (Difference) ?		am580 analog cis equal ester esterifies extremely hepatic homogenates implicate microsomal molar natural negligible pan pmol predominant r2 rars re retinoid retinoids retinol retinyl retro storage trans uab8	ascl2 c4b dab2ip dlk1 eya4 fabp3 fzd9 gas7 hdac9 hoxa11 hoxa5 hoxa9 hoxb13 ihh ipf1 isl1 mest mme pax6 ptgs2 rassf1 scgb3a1 sept5 serpina5 sox1 sox17 tbx1 tff1 thy1
Tagcloud (Intersection) ?