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NOLC1 and USP4
Number of citations of the paper that reports this interaction (PubMedID
11571651
)
0
Data Source:
HPRD
(in vivo)
NOLC1
USP4
Description
nucleolar and coiled-body phosphoprotein 1
ubiquitin specific peptidase 4
Image
No pdb structure
GO Annotations
Cellular Component
Fibrillar Center
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cajal Body
Nucleus
Cytoplasm
Lysosome
Cytosol
Molecular Function
Nucleotide Binding
RNA Binding
Protein Binding
ATP Binding
GTP Binding
Protein-macromolecule Adaptor Activity
Protein Heterodimerization Activity
Molecular Function Inhibitor Activity
Cysteine-type Deubiquitinase Activity
Protein Binding
Peptidase Activity
Cysteine-type Peptidase Activity
Hydrolase Activity
Adenosine Receptor Binding
Identical Protein Binding
Metal Ion Binding
Biological Process
Mitotic Cell Cycle
RRNA Processing
Regulation Of Translation
Nucleolus Organization
Neural Crest Formation
Neural Crest Cell Development
Spliceosomal Tri-snRNP Complex Assembly
Cytoplasmic Translation
Proteolysis
Cellular Response To Starvation
Protein Deubiquitination
Negative Regulation Of Protein Ubiquitination
Regulation Of Protein Stability
Cellular Response To Nutrient Levels
Protein Localization To Cell Surface
TORC1 Signaling
Negative Regulation Of Translational Initiation
Positive Regulation Of Translational Initiation
Negative Regulation Of TORC1 Signaling
Positive Regulation Of TORC1 Signaling
Pathways
TNFR1-induced proapoptotic signaling
Regulation of TNFR1 signaling
TNFR1-induced NF-kappa-B signaling pathway
Ub-specific processing proteases
Drugs
Doxorubicin
Diseases
GWAS
Liver enzyme levels (alkaline phosphatase) (
33972514
)
Smoking initiation (
33082346
)
Triglyceride levels (
32203549
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Crohn's disease (
28067908
)
Glycated hemoglobin levels (
34059833
28898252
)
High light scatter reticulocyte percentage of red cells (
27863252
)
Household income (MTAG) (
31844048
)
Inflammatory bowel disease (
28067908
23128233
)
Intelligence (MTAG) (
29326435
)
Lymphocyte count (
32888494
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Red cell distribution width (
32888494
)
Refractive error (
32231278
)
Reticulocyte count (
27863252
)
Reticulocyte fraction of red cells (
27863252
32888494
)
Sleep duration (short sleep) (
30846698
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Ulcerative colitis (
28067908
25082827
)
Interacting Genes
19 interacting genes:
APP
CEBPA
CEBPB
COIL
CSNK2A1
CSNK2B
E2F4
ERG
GTF2B
ING4
KBTBD8
MDM2
OGT
POLR1A
PRKACA
SRPK2
USP4
YWHAG
YWHAQ
49 interacting genes:
AKT1
ANXA7
ASS1
ATP1B1
ATP1B3
BDKRB2
BRAP
CDKN1A
CIAO2B
DLC1
HDAC2
IGKV2D-29
IRF4
LAMA5
LGALS1
MAP3K7
NLK
NOLC1
NPC2
PCNA
PDK1
PGM1
PLA2G2A
PLOD1
PPIA
PRPF3
PSAP
PSMA6
PSMC5
PSMD11
RB1
RBBP8
RBL1
RBL2
RCC1
RHEB
RNPS1
SMAD4
SMN1
TK1
TP53BP2
TRAF2
TRIM21
TRIM54
TRIM55
TRIM63
UBC
USP21
USP28
Entrez ID
9221
7375
HPRD ID
03864
04598
Ensembl ID
ENSG00000166197
ENSG00000114316
Uniprot IDs
B2RAU8
Q14978
Q96J17
Q08AK7
Q13107
PDB IDs
2Y6E
5CTR
Enriched GO Terms of Interacting Partners
?
Protein Domain Specific Binding
Nucleus
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Proteolysis
Regulation Of Protein Catabolic Process
Negative Regulation Of Translational Initiation
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein Modification Process
Chromatin Binding
TORC1 Signaling
Intracellular Signal Transduction
C/EBP Complex
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Protein Metabolic Process
Regulation Of Protein Metabolic Process
Macromolecule Metabolic Process
TOR Signaling
Regulation Of Primary Metabolic Process
CHOP-C/EBP Complex
Protein Kinase CK2 Complex
Symbiont-mediated Disruption Of Host Cell PML Body
Negative Regulation Of Macromolecule Metabolic Process
Protein-containing Complex Assembly
Regulation Of TORC1 Signaling
Regulation Of Translation
Regulation Of Translational Initiation
Positive Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Identical Protein Binding
Cellular Response To Nutrient Levels
Negative Regulation Of Metabolic Process
Nucleoplasm
Negative Regulation Of Biosynthetic Process
Protein-containing Complex Organization
Regulation Of Macromolecule Metabolic Process
Regulation Of Gene Expression
Response To Nutrient Levels
RNA Polymerase II Transcription Regulator Complex
Positive Regulation Of Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Cellular Component Assembly
Negative Regulation Of Proteolysis
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Translational Initiation
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of TOR Signaling
Regulation Of Glycolytic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of Lipid Kinase Activity
Intracellular Signal Transduction
Nucleoplasm
Regulation Of Phosphorus Metabolic Process
Regulation Of Catalytic Activity
Intracellular Signaling Cassette
Macromolecule Metabolic Process
Extracellular Exosome
PCNA-p21 Complex
Regulation Of Kinase Activity
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Intracellular Signal Transduction
Response To Stress
Nucleus
Identical Protein Binding
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Regulation Of Phosphorylation
Positive Regulation Of Catalytic Activity
TORC1 Signaling
Regulation Of Cell Cycle
Apoptotic Signaling Pathway
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Deoxyribonuclease Activity
Negative Regulation Of Cell Cycle G1/S Phase Transition
Negative Regulation Of Cell Cycle Phase Transition
Protein-containing Complex
Cytoplasm
Cytosol
Response To External Biotic Stimulus
Negative Regulation Of Cell Cycle
Signal Transduction
Positive Regulation Of Potassium Ion Import Across Plasma Membrane
Sulfate Binding
Cellular Response To Stress
G1/S Transition Of Mitotic Cell Cycle
Regulation Of G1/S Transition Of Mitotic Cell Cycle
TOR Signaling
Cell Cycle G1/S Phase Transition
Positive Regulation Of Sodium Ion Transport
NF-kappaB Binding
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Potassium Ion Import
Cellular Response To Chemical Stress
Protein Modification Process
Negative Regulation Of Cell Cycle Process
Epithelial Cell Differentiation
DNA-binding Transcription Factor Binding
Positive Regulation Of Interleukin-2 Production
Cell Differentiation
Regulation Of Cell Cycle G1/S Phase Transition
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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