NOLC1

Description		nucleolar and coiled-body phosphoprotein 1
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytoplasm Cajal Body
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding ATP Binding GTP Binding Protein-macromolecule Adaptor Activity Protein Heterodimerization Activity Molecular Function Inhibitor Activity
	Biological Process	Mitotic Cell Cycle RRNA Processing Regulation Of Translation Nucleolus Organization Neural Crest Formation Neural Crest Cell Development
Pathways
Drugs		Doxorubicin
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Smoking initiation ( 33082346) Triglyceride levels ( 32203549)
Novel Interacting Genes		1 novel interacting genes: DPCD
Interacting Genes		19 interacting genes: APP CEBPA CEBPB COIL CSNK2A1 CSNK2B E2F4 ERG GTF2B ING4 KBTBD8 MDM2 OGT POLR1A PRKACA SRPK2 USP4 YWHAG YWHAQ
Entrez ID		9221
HPRD ID		03864
Ensembl ID		ENSG00000166197
Uniprot IDs		B2RAU8 Q14978 Q96J17
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Domain Specific Binding Nucleus Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Regulation Of Protein Catabolic Process Negative Regulation Of Translational Initiation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Modification Process Chromatin Binding TORC1 Signaling Intracellular Signal Transduction C/EBP Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Metabolic Process Regulation Of Protein Metabolic Process Macromolecule Metabolic Process TOR Signaling Regulation Of Primary Metabolic Process CHOP-C/EBP Complex Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Macromolecule Metabolic Process Protein-containing Complex Assembly Regulation Of TORC1 Signaling Regulation Of Translation Regulation Of Translational Initiation Positive Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Identical Protein Binding Cellular Response To Nutrient Levels Negative Regulation Of Metabolic Process Nucleoplasm Negative Regulation Of Biosynthetic Process Protein-containing Complex Organization Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Response To Nutrient Levels RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Cellular Component Assembly Negative Regulation Of Proteolysis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Translational Initiation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of TOR Signaling Regulation Of Glycolytic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression
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