OXNAD1 and SEC13

		OXNAD1	SEC13
Description		oxidoreductase NAD binding domain containing 1	SEC13 homolog, nuclear pore and COPII component
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Kinetochore Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Lysosome Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Membrane COPII Vesicle Coat Nuclear Pore Outer Ring Cytoplasmic Vesicle GATOR2 Complex Extracellular Exosome
	Molecular Function	Protein Binding Oxidoreductase Activity	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process		Protein Import Into Nucleus Intracellular Protein Transport Nucleocytoplasmic Transport Protein Transport Vesicle-mediated Transport Cellular Response To Nutrient Levels Positive Regulation Of TOR Signaling Protein Exit From Endoplasmic Reticulum MRNA Transport COPII-coated Vesicle Cargo Loading COPII-coated Vesicle Budding Negative Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling
Pathways			ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly COPII-mediated vesicle transport MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation Amino acids regulate mTORC1 EML4 and NUDC in mitotic spindle formation SARS-CoV-2 activates/modulates innate and adaptive immune responses Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		4 interacting genes: CAPNS2 FKBP7 FSD2 IFT20	14 interacting genes: ADGRF5 CFAP43 CLDN12 EGFR HAPLN2 HSPB1 LTB4R2 NUP98 RAB11A SEC16B SEC31A TRAF5 WDR44 WEE2-AS1
Entrez ID		92106	6396
HPRD ID		14446	02538
Ensembl ID		ENSG00000154814	ENSG00000157020
Uniprot IDs		C9JLB7 Q96HP4	A8MWR8 P55735
PDB IDs			3BG0 3BG1 5A9Q 7PEQ 7R5J 7R5K 7UHY
Enriched GO Terms of Interacting Partners?		Gamma-aminobutyric Acid:sodium:chloride Symporter Activity Gamma-aminobutyric Acid Transmembrane Transporter Activity Gamma-aminobutyric Acid Import Amino Acid:sodium Symporter Activity Gamma-aminobutyric Acid Transport Acidic Amino Acid Transport Inorganic Anion Import Across Plasma Membrane Neurotransmitter Transport Transport Across Blood-brain Barrier Amino Acid Transmembrane Transport Symporter Activity Associative Learning Taurine:sodium Symporter Activity Taurine Transmembrane Transporter Activity Opsin Transport Intraciliary Transport Particle GABA-ergic Synapse Sodium:chloride Symporter Activity Gamma-aminobutyric Acid Reuptake Alanine Transmembrane Transporter Activity Kinociliary Basal Body Amino Acid Transport COPII-coated Vesicle Budding Import Across Plasma Membrane Sodium Ion Transmembrane Transport Taurine Transmembrane Transport MRF Binding Calpain Complex Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Dendrite Terminus Opsin Binding Learning Sodium Ion Transport	Regulation Of Protein Kinase C Signaling Establishment Of Protein Localization Golgi Vesicle Transport Cellular Localization Protein Transport Endoplasmic Reticulum Exit Site Golgi To Plasma Membrane Protein Transport Positive Regulation Of Cilium Assembly
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