ZMYM5 and ZNRD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZMYM5	ZNRD2
Description		zinc finger MYM-type containing 5	zinc ribbon domain containing 2
Image
GO Annotations	Cellular Component	Nucleus	Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Mitotic Cell Cycle Cell Division
Pathways
Drugs
Diseases
GWAS		Alcohol use disorder (consumption score) ( 30940813) Arterial stiffness (brachial-ankle pulse wave velocity) ( 32790701) Methadone dose in opioid dependence ( 28115739)	Glaucoma (primary open-angle) ( 33627673)
Interacting Genes		33 interacting genes: - APP CAMK2B CARD9 CBS CREBBP DAPK1 DES FADD FBXO7 FTCD GTF2IRD1 HMBOX1 HOMER1 ITSN1 LCE3B LRRK2 MFHAS1 MORC3 PAX5 PDE9A PRMT1 SKIL SNIP1 SUMO1 SUMO2 TFG TRAF2 TRAF4 TRIP13 UBQLN1 ZBTB26 ZNRD2	27 interacting genes: ACTN2 CATSPERT CCDC33 CCNH CCT2 CCT3 CCT5 CCT7 FNDC11 FXR2 IL16 INCA1 MYO15B NME6 NOC4L PIAS2 RNF115 RNF4 SNAPC5 STAT3 SUMO1P1 TRAF3IP3 TRAPPC6A UBC UBE2I VTA1 ZMYM5
Entrez ID		9205	10534
HPRD ID		10324	06921
Ensembl ID		ENSG00000132950	ENSG00000173465
Uniprot IDs		Q9UJ78	G3V1B8 O60232
PDB IDs		2DAS	6HCZ
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Regulation Of JNK Cascade Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Ubiquitin Protein Ligase Binding Positive Regulation Of Cell Communication Positive Regulation Of Signaling Signaling Adaptor Activity Positive Regulation Of Protein Metabolic Process PML Body Positive Regulation Of Proteolysis Regulation Of MAPK Cascade Response To Stress Cysteine Biosynthetic Process From Serine Cystathionine Beta-synthase Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Protein-containing Complex Organization Regulation Of Apoptotic Process Regulation Of Postsynapse Organization Cytosol Regulation Of Apoptotic Signaling Pathway S-adenosyl-L-methionine Binding Enzyme Binding Regulation Of Programmed Cell Death Cysteine Biosynthetic Process Via Cystathionine Carbon Monoxide Binding Protein-containing Complex Assembly Positive Regulation Of MAPK Cascade Cysteine Biosynthetic Process Homocysteine Catabolic Process Hydrogen Sulfide Biosynthetic Process Cellular Response To Stress Presynaptic Cytosol Positive Regulation Of Signal Transduction Postsynaptic Cytosol Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Multicellular Organismal Process L-serine Catabolic Process Transsulfuration Nitrite Reductase (NO-forming) Activity Cerebellum Morphogenesis Hydrogen Sulfide Metabolic Process L-cysteine Catabolic Process Nitric Oxide Binding Tumor Necrosis Factor Receptor Binding Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of JNK Cascade	Positive Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Protein Localization To Cajal Body Chaperonin-containing T-complex Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Binding Of Sperm To Zona Pellucida ATP-dependent Protein Folding Chaperone Sperm-egg Recognition Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Biosynthetic Process Regulation Of Telomere Maintenance Via Telomere Lengthening Cell-cell Recognition Protein Folding Chaperone Positive Regulation Of Telomere Maintenance Cell Body Regulation Of DNA Biosynthetic Process Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Chromosome Organization PML Body Regulation Of Telomere Maintenance Unfolded Protein Binding Protein Stabilization Regulation Of Chromosome Organization Cell Recognition Zona Pellucida Receptor Complex Protein Sumoylation Regulation Of Protein Localization To Nucleus Protein Tag Activity Regulation Of Protein Stability Protein Folding Transcription Factor Binding SUMO Transferase Activity Protein Modification By Small Protein Conjugation Positive Regulation Of DNA Metabolic Process Positive Regulation Of Organelle Organization Actin Filament Uncapping SUMO Conjugating Enzyme Activity RNA Polymerase II General Transcription Initiation Factor Activity Protein K11-linked Ubiquitination Post-translational Protein Modification Microtubule
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