COG7 and DCTN5

Data Source: HiPPIP (Novel)

		COG7	DCTN5
Name		component of oligomeric golgi complex 7	dynactin subunit 5
Structure		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleolus Golgi Apparatus Membrane Golgi Transport Complex Trans-Golgi Network Membrane	Chromosome, Centromeric Region Kinetochore Nucleoplasm Chromosome Cytoplasm Centrosome Cytosol Cytoskeleton Dynactin Complex Nuclear Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Retrograde Transport, Vesicle Recycling Within Golgi Protein Glycosylation Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Protein Transport Protein Localization To Organelle Protein Localization To Golgi Apparatus Protein Stabilization Glycosylation	Ventricular Septum Development Aorta Development Coronary Vasculature Development
Pathways		COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
Diseases		Congenital disorders of glycosylation (CDG) type II	None
GWAS		Egg allergy ( 25710614 )	Bipolar disorder ( 17554300 )
Novel Interactors		2 novel interactors: DCTN5 NFKBIE	5 novel interactors: C16orf82 CHP2 COG7 EARS2 KDM8
Interacting Genes		8 interacting genes: COG4 COG5 EMILIN1 HNRNPD KIFC3 MEOX2 TAX1BP1 ZNF471	5 interacting genes: DYNLL1 FATE1 NINL PMEPA1 RBPMS
Entrez ID		91949	84516
HPRD ID		07373	14551
Ensembl ID		ENSG00000168434	ENSG00000166847
Uniprot IDs		A0A0S2Z652 P83436	Q9BTE1
PDB IDs		Not available	5NW4
GO Terms Enriched among Interactors		Golgi Transport Complex Retrograde Transport, Vesicle Recycling Within Golgi Golgi Organization Intra-Golgi Vesicle-mediated Transport Hepatocyte Dedifferentiation Cellular Response To Putrescine	None